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Noninvasive Assessment of Trabecular Bone Architecture and The Competence of Bone (Hardcover, 2001 ed.)
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Noninvasive Assessment of Trabecular Bone Architecture and The Competence of Bone (Hardcover, 2001 ed.)
Series: Advances in Experimental Medicine and Biology, 496
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Sharmila Majumdar In the area of osteoporosis and skeletal changes,
it is currently accepted that bone mineral density (BMD), widely
used for screening, monitoring and assessing therapeutic efficacy,
does not adequately explain the pathogenesis of osteoporosis, the
process of aging, or the therapeutic efficacy of various
treatments. In this context, trabecular micro- architecture has
enormous potential to contribute to understanding the
pathophysiology of osteopor.osis and therapy assessment. The use
and value of noninvasive imaging and quantitative image analysis
and processing of trabecular bone micro-architecture have increased
dramatically due to recent advances in instrumentation and
software. This emerging field is diverse, interdisciplinary, and
encompasses many different imaging modalities. Interested
researchers include those involved in technique development, basic
science and animal studies, as well as clinical researchers and
practicing physicians. With the growth of this area of research, a
group of investigators at the 11th Interna- tional Workshop of Bone
Densitometry, 1 concluded that a forum dedicated to this matter was
urgently needed. With this agenda, Dr. Peter Ruegsegger organized
the first sympo- 2 sium on conjunction with the 10th Conference of
the European Society of Biomechanics. The symposium on Bone
Architecture and Competence was a two-hourlong event which resulted
in five chapters in Bone Research and Biomechanics, edited by G.
Lowet, P. Ruegsegger, H. Weinans, and A. Meunier, published by lOS
Press, 1997. The second symposium was held as a pre-symposium to
the 12th Workshop on Bone Denistometry,3 and flourished as a
daylong event.
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