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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Genetics (non-medical)
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Genetics of Bacteria (Hardcover, 2013 ed.)
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Genetics of Bacteria (Hardcover, 2013 ed.)
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Described as the earliest, simplest life forms, with unlimited
metabolic versatility, bacteria are ideally suited to answer some
very fundamental questions on life and its processes. They have
been employed in almost all fields of biological studies, including
Genetics. The whole edifice of science of Genetics centers around
three processes: the generation, expression, and transmission of
biological variation, and bacteria offer immediate advantages in
studying all the three aspects of heredity. Being haploid and
structurally simple, it becomes easy to isolate mutations of
various kinds and relate them to a function. The availability of
such mutants and their detailed genetic and biochemical analyses
lead to a gamut of information on gene expression and its
regulation. While studying the transmission of biological
variation, it is clear that unlike their eukaryotic counterpart, a
more genetic approach needs to be employed. Transmission of genetic
information in most eukaryotic organisms rests on sexual
reproduction that allows the generation of genetically variable
offspring through the process of gene recombination. Even though
bacteria show an apparent preference for asexual reproduction, they
too have evolved mechanisms to trade their genetic material. In
fact, bacteria not only could acquire many genes from close
relatives, but also from entirely distant members through the
process of horizontal gene transfer. Their success story of long
evolutionary existence will stand testimony to these mechanisms.
While teaching a course on Microbial Genetics to the post-graduate
students at Delhi University, it was realized that a book devoted
to bacterial genetics may be very handy to the students,
researchers, and teachers alike. A strong foundation in genetics
also helps in comprehending more modern concepts of molecular
biology and recombinant DNA technology, always a favorite with the
students and researchers. Planning the format of the book, emphasis
has been laid on the generation and transmission of biological
variability. The omission of expression part is indeed intentional
because lots of information is available on this aspect in any
modern biology book. The contents are spread over seven chapters
and the text is supported with figures/tables wherever possible.
The endeavor has been to induce the readers to appreciate the
strength of bacterial genetics and realize the contribution of
these tiny organisms to the growth of biological sciences as a
whole and genetics in particular.
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