Microarray Methods for Drug Discovery (Hardcover, 2010 ed.)

The postgenomic era presents a multitude of challenges for scientists in all areas of science. The information overload from new discoveries in genomics and proteomics highlight how little we really know about the functioning of a cell. The advent of Next-Generation Sequencing technologies promises to make our genetic blueprint available to the common man. The availability of the plethora of biological information has lead to the devel- ment of new areas of science and the coining of new "omics" terms including transcr- tomics, methylomics, toxicogenomics, pharmacogenomics, metabolomics, lipidomics, and so on. Remarkable research is being conducted to understand the various aspects of human health and how processes like histone modifcations, promoter usage, alternative splicing, posttranscriptional, and posttranslational modifcations contribute to disease. The advent of systems biology has unifed chemists and biochemists alike in the struggle to eradicate or treat human disease. Microarrays have blossomed into a fast developing and cutting-edge technology that promises to become a major component of personalized medicine. The 1990s witnessed a boom in many areas including genome sequencing, combinatorial chemistry, and c- puters, all of which have contributed to the development of microarray technology from its infancy into a mature tool. The growing potential of this tool is evident from the n- ber of publications since 1991 when Fodor et al. of Affymax (now Affymetrix) frst described the microarray prototype.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 632
Release date:	March 2010
First published:	2010
Editors:	Sridar V. Chittur
Dimensions:	254 x 178 x 17mm (L x W x T)
Format:	Hardcover
Pages:	285
Edition:	2010 ed.
ISBN-13:	978-1-60761-662-7
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Other branches of medicine > Pharmacology > General Promotions
LSN:	1-60761-662-9
Barcode:	9781607616627

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