Bile Acids and Their Receptors (Hardcover, 1st ed. 2019)

This book focusses on the latest results related to the field of bile acids as signaling molecules and describes how these receptors have become a major pharmacological target. It covers all major areas of research in this field, from genetics, chemistry, in silico modeling, molecular biology to clinical applications, offering a cross-country view of the functional role of bile acids as signaling molecules, virtually acting on all major areas of metabolism. While FXR and GPBAR1 are essential bile acid sensors that integrate the de novo bile acid synthesis with intestinal microbiota and liver metabolism, in a broader sense, BARs play a pathogenic role in the development of common human alignments including liver, intestinal and metabolic disorders, such as steatosis (NAFLD) and steato-hepatitis (NASH), diabetes, obesity and atherosclerosis.

General

Imprint:	Springer Nature Switzerland AG
Country of origin:	Switzerland
Series:	Handbook of Experimental Pharmacology, 256
Release date:	September 2019
First published:	2019
Editors:	Stefano Fiorucci • Eleonora Distrutti
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	378
Edition:	1st ed. 2019
ISBN-13:	978-3-03-022004-4
Categories:	Books > Medicine > Clinical & internal medicine > Gastroenterology Books > Medicine > Clinical & internal medicine > Hepatology Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > General Books > Medicine > Clinical & internal medicine > Endocrinology > General Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	3-03-022004-4
Barcode:	9783030220044

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