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The Artery and the Process of Arteriosclerosis - Measurement and Modification, The second half of the Proceedings of an Interdisciplinary Conference on Fundamental Data on Reactions of Vascular Tissue in Man, April 19-25, 1970, Lindau, West Germany (Paperback, Softcover reprint of the original 1st ed. 1972)
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The Artery and the Process of Arteriosclerosis - Measurement and Modification, The second half of the Proceedings of an Interdisciplinary Conference on Fundamental Data on Reactions of Vascular Tissue in Man, April 19-25, 1970, Lindau, West Germany (Paperback, Softcover reprint of the original 1st ed. 1972)
Series: Advances in Experimental Medicine and Biology, 16B
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Substantial progress toward reconciling disparate theories of the
pathogenesis of arteriosclerosis was recorded in Volume I of this
book. the proceedings of an interdisciplinary workshop conference
held at Lindau. Germany, April 19-25, 1970. Strong evidence was ad
duced that the early stages of arteriosclerosis consist of intimal
proliferation similar to that associated with the increase in
arteri al size and caliber that characterizes normal growth. The
findings described recall a theory proposed by Richard Thoma (Thoma
and Kaefer, 1889) of Heidelberg toward the end of the nineteenth
century. He sug gested that the pathogenesis of arteriosclerosis
began with intimal thickening that was initially adaptive. Past a
certain point, how ever, the thickening compromised the nutrition
of the artery wall, leading inevitably to degenerative changes. In
1944 Hueper (Hueper, 1944), reemphasized the threat to the nu
tritional support of the artery and proposed that the many
etiologic factors capable of inducing arterial atheroma did so
through the final common pathway of interfering with oxidative
mechanisms in the vessel wall. Thus, it is proposed that
arteriosclerosis is basically an aspect of the "behavior" of the
artery. The nature of the lesion, therefore, depends more on the
biochemical and structural response capabilities of the tissue
itself than on the characteristics of the various etiologic agents.
The idea that arteriosclerosis begins as uncontrolled or disturbed
adaptive behavior was shared by Duff and also by Winternitz (Duff,
1954; Winternitz, 1954)."
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Series: |
Advances in Experimental Medicine and Biology, 16B |
Release date: |
November 2012 |
First published: |
1972 |
Authors: |
Stewart Wolf
|
Dimensions: |
244 x 170 x 18mm (L x W x T) |
Format: |
Paperback
|
Pages: |
337 |
Edition: |
Softcover reprint of the original 1st ed. 1972 |
ISBN-13: |
978-1-4615-8227-4 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Cardiovascular medicine
|
LSN: |
1-4615-8227-X |
Barcode: |
9781461582274 |
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