In recent years, the development of new technologies capable of
monitoring genome function has resulted in fewer hopeful estimates
and increasingly solid depictions of genome output from individual
samples. Genomics in Endocrinology focuses on exciting new advances
in endocrinology resulting from DNA microarray studies and includes
a comprehensive introduction to the use of DNA microarrays in
endocrinology. The volume provides the basis for further
understanding of the usefulness of microarray analyses in
endocrinology research. Topics discussed are the methodology of DNA
microarrays and general methods for the analysis of microarray
data, as well as studies of a wide variety of normal and abnormal
endocrine cells.
In the introductory chapter, the volumea (TM)s editors describe
several issues in hypothesis formulation, experimental design, data
analysis, and follow-up studies that may corroborate, validate, and
extend hypotheses gained through microarray analyses. The
contributed chapters span a variety of applications that we have
divided into the areas of (1) genomic insights into molecular
mechanisms responsible for hormone action, (2) genomic
characterizations of endocrine producing tissues, and (3) genomic
manifestations of diseases of hormonal systems.
A volume on the cutting-edge of technology, Genomics in
Endocrinology will provide researchers with an authoritative volume
on the most recent advances in monitoring genome function.
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