In recent years, major developments have increased understanding
of various genetic and epigenetic regulatory processes that are
critical for the generation of B cell repertoires. These include
the role of chromatin regulation and nuclear organization in
understating the IgH gene regulation. These proceedings highlight
recent developments in lymphocyte development, Ig gene
rearrangements and somatic hypermutation, chromatin structure
modification, B lymphocyte signaling and fate, receptor editing,
and autoimmunity.
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