Designer Microbial Cell Factories: Metabolic Engineering and
Applications, the latest release in the Current Developments in
Biotechnology and Bioengineering series, provides a detailed
overview of the biotechnological approaches and strategies used to
generate engineered microbes and to facilitate the acceleration,
modulation and diversion of metabolic pathways to get desired
output such as production of value-added compound or biodegradation
of xenobiotic pollutant. The book also highlights applied aspects
of designer microbes in fields as diverse as agriculture,
pharmaceuticals and bioremediation. Designer microbes generated
through reprogramming the microbial cell factories (MCFs) provide
an edge over their natural counterparts in terms of increased
molecular diversity and selective chemistry. These bugs are
becoming instrumental in several areas, including agriculture,
environment and human health. Engineering microbes through directed
evolution not only gives freedom from evolutionary constrains but
also allow introduction of regulated and foreseeable functions into
MCFs.
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