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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Bioactive Lipid Mediators - Current Reviews and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
Loot Price: R5,428
Discovery Miles 54 280
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Bioactive Lipid Mediators - Current Reviews and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
Expected to ship within 10 - 15 working days
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This book summarizes the most recent progress in the studies of
lipid mediators from the molecular to clinical level and introduces
newly created tools for analysis including imaging mass
spectrometry. Comprising 29 chapters divided into four major parts,
the book describes the molecular natures of enzymes, transporters,
and receptors for lipid mediators (Part I), the function of lipid
mediators in Drosophila and Zebrafish (Part II), the relationships
between lipid mediators and various diseases (Part III), and
detailed procedures of extraction, preparation, and quantification
of lipid mediators (Part IV). Research on lipid mediators initially
started with analysis of the action of aspirin, and subsequent
biochemical experiments identified many enzymes and receptors
responsible for the biosynthesis and signal transduction of
individual lipid mediators. Through the phenotypic analyses of
transgenic and knockout mice, it has been shown that the
dysregulation of some lipid mediators causes inflammatory, immune,
or oncogenic disorders. Lipid mediators have attracted increased
attention because their structures are conserved among different
species, and their biosynthetic and signaling pathways have been
deciphered at the molecular level. Many drugs that target lipid
mediators are already being used in hospitals, and this book
suggests further possibilities for development of a wide variety of
such drugs. Very recently, highly sensitive mass spectrometry has
begun to be used to identify novel lipid mediators that are present
only in trace amounts in tissues but with robust biological
activity. Written by international experts, this book provides
readers a comprehensive view of lipid mediators and related topics
and helps in the process of determining research targets for the
near future.
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