Thyroid Gland and Chromium Toxicity (Paperback)

Toxicity due to heavy metals is of major concern in Pakistan. Mercury, cadmium, chromium, arsenic, lead, zinc and copper concentrations have increased to alarming levels in the water, soil and air which have become large dumps of industrial effluents. Physiologically, heavy metals can profoundly affect the functioning of the endocrine system and in Pakistan, thyroid related diseases are also very common. Chromium in hexavalent form is highly toxic and a known carcinogen, however as opposed to the trivalent form, its toxic effects on the thyroid structure and function are relatively unexplored. Acute exposure to chromium (VI) can occur in the occupational set up. The present study, therefore, investigated the thyroid gland structure and function following intraperitoneal administration of potassium dichromate (Cr-VI) in laboratory rats.Diverse techniques were employed during the study. The results give an insight to the toxic effects of hexavalent chromium on the thyroid gland and describe how the metal interferes with the functioning of the gland; not only with its morphology but also at cellular and molecular levels.

General

Imprint:	VDM Verlag
Country of origin:	Germany
Release date:	July 2010
First published:	July 2010
Authors:	Tariq Mahmood • Irfan Zia Qureshi
Dimensions:	229 x 152 x 8mm (L x W x T)
Format:	Paperback - Trade
Pages:	132
ISBN-13:	978-3-639-25661-1
Categories:	Books > Science & Mathematics > Biology, life sciences > Zoology & animal sciences > General
LSN:	3-639-25661-1
Barcode:	9783639256611

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