Decellularized Extracellular Matrix - Characterization, Fabrication and Applications (Hardcover)

The extracellular matrix (ECM) supports cells and regulates various cellular functions in our body. The native ECM promises to provide an excellent scaffold for regenerative medicine. In order to use the ECM as a scaffold in medicine, its cellular fractions need to be removed while retaining its structural and compositional properties. This process is called decellularization, and the resulting product is known as the decellularized extracellular matrix (dECM). This book focuses on the sources of dECM and its preparation, characterization techniques, fabrication, and applications in regenerative medicine and biological studies. Using this book, the reader will gain a good foundation in the field of ECM decellularization complemented with a broad overview of dECM characterization, ranging from structural observation and compositional assessment to immune responses against dECM and applications, ranging from microfabrication and 3D-printing to the application of tissue-derived dECM in vascular grafts and corneal tissue engineering etc. The book closes with a section dedicated to cultured cell dECM, a complementary technique of tissue-derived dECM preparation, for application in tissue engineering and regenerative medicine, addressing its use in stem cell differentiation and how it can help in the study of the tumor microenvironment as well as in clinical trials of peripheral nerve regeneration.

General

Imprint:	Royal Society of Chemistry
Country of origin:	United Kingdom
Series:	Biomaterials Science Series, Volume 6
Release date:	December 2019
First published:	2020
Editors:	Tetsuji Yamaoka • Takashi Hoshiba
Dimensions:	234 x 156 x 31mm (L x W x T)
Format:	Hardcover - Unsewn / adhesive bound
Pages:	352
ISBN-13:	978-1-78801-467-0
Categories:	Books > Science & Mathematics > Chemistry > Organic chemistry > Polymer chemistry Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Chemical engineering Books > Professional & Technical > Mechanical engineering & materials > Materials science > General
LSN:	1-78801-467-7
Barcode:	9781788014670

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