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Rational Drug Design - Methods and Protocols (Hardcover, 1st ed. 2018)
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Rational Drug Design - Methods and Protocols (Hardcover, 1st ed. 2018)
Series: Methods in Molecular Biology, 1824
Expected to ship within 9 - 15 working days
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This volume covers several aspects of rational drug design, such as
synthesis of novel bioactive drugs; development and application of
new methodologies; computational methods valuable for the
establishment of new approaches in drug discovery; and the effects
of physical-chemical and ADMET properties of the designed potential
drugs. Chapters guide readers through amyloid deposits, Saturation
Transfer Difference (STD) NMR, methods on bioguided design, the
importance of lipophilicity in drug design, ADMET, FRET, structural
biology, and homology modeling. Written in the highly successful
Methods in Molecular Biology series format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Authoritative and cutting-edge, Rational Drug
Design: Methods and Protocols aims to ensure successful results in
the further study of this vital field.
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