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Nanomaterials for Liquid Chromatography and Laser Desorption/Ionization Mass Spectrometry (Hardcover, 2015 ed.)
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Nanomaterials for Liquid Chromatography and Laser Desorption/Ionization Mass Spectrometry (Hardcover, 2015 ed.)
Series: Springer Theses
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Tian Lu's dissertation describes major advances in ultrathin-layer
chromatography (UTLC), liquid chromatography and surface-assisted
laser desorption ionization (SALDI), and matrix-enhanced SALDI
(ME-SALDI) mass spectrometry. Lu describes the fabrication of
electrospun polyvinyl alcohol (PVA) UTLC plates using an in-situ
crosslinking electrospinning technique. The author improved the
efficiency of PVA plates greatly compared to the efficiency of
silica HPTLC plates. Also highlighted in this thesis is an
edge-plane based ordered-carbon surface that provides unique
selectivity in liquid chromatography. Further developments include
polar analytes, such as amino acids, nucleotides and nucleosides
which can be well-retained and separated in the edge-plane
ordered-carbon stationary phase. Also, the author studied and
detected mass spectra of organic polymers as high as 900,000 Da,
the highest molecular weight that has been studied by SALDI to date
using the carbon nanofibrous substrate. This thesis has led to a
number of publications in high-impact journals.
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