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Cell Cycle Control - Mechanisms and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2005)
Loot Price: R2,958
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Cell Cycle Control - Mechanisms and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2005)
Series: Methods in Molecular Biology, 296
Expected to ship within 10 - 15 working days
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The fundamental question of how cells grow and divide has perplexed
biologists since the development of the cell theory in the mid-19th
century, when it was recognized by Virchow and others that "all
cells come from cells." In recent years, considerable effort has
been applied to the identification of the basic molecules and
mechanisms that regulate the cell cycle in a number of different
organisms. Such studies have led to the elucidation of the central
paradigms that underpin eukaryotic cell cycle control, for which
Lee Hartwell, Tim Hunt, and Paul Nurse were jointly awarded the
Nobel Prize for Medicine and Physiology in 2001 in recognition of
their seminal contributions to this field. The importance of
understanding the fundamental mechanisms that modulate cell
division has been reiterated by relatively recent discoveries of
links between cell cycle control and DNA repair, growth, cellular
metabolism, development, and cell death. This new phase of
integrated cell cycle research provides further challenges and
opportunities to the biological and medical worlds in applying
these basic concepts to understanding the etiology of cancer and
other proliferative diseases.
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