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Books > Science & Mathematics > Chemistry > Organic chemistry
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Experimental Methods in Organic Fluorine Chemistry (Hardcover)
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Experimental Methods in Organic Fluorine Chemistry (Hardcover)
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In the fields of biologically active materials and functional
materials, fluorinated organic materials are becoming a focus of
significant interest. Over the past decade synthetic methodologies
and reagents in fluorine chemistry have been developed, especially
stereocontrolled synthetic methods, enzymatic resolution to
synthesize enantiomers, fluoromethylated reagents, and fluorination
reagents. These methods have contributed to the opening of new
pathways for fluorinated materials. However, few fluorinated
materials have been put to commercial use. Furthermore, there
remain problems to be solved, such as the handling of the
materials, availability of reagents and selectivity (stereo-,
regio-, and/or chemoselectivity). Research chemists, technical
engineers, and graduate students in all branches of chemistry,
pharmaceutics, and material science interested in fluorinated
materials need to know detailed experimental procedures of how to
synthesize the target fluorinated materials.
This volume summarizes the chemical and microbial methods for
obtaining functionalized fluorinated materials for use as building
blocks; detailed experimental methods (reaction conditions,
solvent, temperature, handling techniques, etc.); and the
stereoview (possible absolute configuration) of the structures with
spectral data. Mono-, di-, tri-, and polyfluorinated materials
derived from fluorinating agents, fluoromethylated reagents and
building blocks are summarized. A chemical name index, molecular
formula index, and reagent index are also included. The publication
of this monograph will provide access to the enormous possibilities
in fluorine chemistry, biological material chemistry, and
functionalized material chemistry.
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