During the past few decades, it has become increasingly apparent
that heredity is not the sole determining factor in disease
development, such as cancer. This landmark work covers a wide array
of aspects in the relatively new area of epigenetics, ranging from
its role in the basic mechanisms of tumorigenesis, to the newest
epigenetic drugs being developed and used for cancer therapy.
Cancer Epigenetics presents in-depth discussions of DNA
methylation alterations, histone and RNA modifications, and
nucleosome remodeling, which are all intimately involved in the
formation of tumors. It also analyzes metabolic influences on
cancer epigenetics and advances in epigenetic cancer gene
therapy.
Discusses the Latest Advances in the Role of Epigenetics in
Tumor Initiation, Progression, and Metastasis
With stand-alone chapters written by research pioneers in the
field, this definitive resource covers- DNA methylation and cancer
Histone modifications in cancer Emerging areas of cancer
epigenetics Epigenetics in the diagnosis, prognosis, and therapy of
cancer Future directions in epigenetic cancer research
Bringing together different topics into a single compilation,
this text is a prime resource for those with interests ranging from
the basic mechanisms of tumor biology to cancer therapy. It also
serves as a core textbook for advanced courses with a focus on
genetic diseases, molecular biology, and/or cancer. This seminal
work answers the call for a thorough and authoritative reference
that covers the critical and contemporary aspects of this
revolutionary field.
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