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Stress-Inducible Cellular Responses (Paperback, Softcover reprint of the original 1st ed. 1996)
Loot Price: R1,624
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Stress-Inducible Cellular Responses (Paperback, Softcover reprint of the original 1st ed. 1996)
Series: Experientia Supplementum, 77
Expected to ship within 10 - 15 working days
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"Stress-Inducible Cellular Responses" are essential for survival of
cells of all species under adverse conditions. At the molecular
level this is ac- complished by a number of essential proteins all
of which are involved in various aspects of cellular homeostasis
through protective or adaptive func- tions. Interestingly,
molecules such as heat shock proteins have properties as molecular
chaperones and are involved in multiple stages of a protein
biogenesis beginning with synthesis and involvement in the
subsequent events of folding, translocation, and degradation. Heat
shock proteins have a critical role to stabilize folding
intermediates and to prevent protein aggregation. In addition,
stress-proteins serve as targets for immune re- sponses in immune
homeostasis and during infections. The term Stress Response
reflects the rapid growth and breadth of this field which includes
the molecular and cellular response to drugs, UV irra- diation,
oxidative stress, and environmental toxins. Radical scavengers such
as superoxide dismutases and inducible regulatory proteins of
metall- ic ion status such as ferritin and protein disulfide
isomerases are also con- sidered within the frame of stress
proteins and represent a new and growing class of stress responses.
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