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Steatohepatitis (NASH and ASH) (Hardcover, 2001 ed.)
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Steatohepatitis (NASH and ASH) (Hardcover, 2001 ed.)
Series: Falk Symposium, 121
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This book is the proceedings of the Falk Symposium No. 121 on
'Steatohepatitis (NASH and ASH)', held in Den Haag, The
Netherlands, on October 14-15, 2000. The histological features of
what we now call non-alcoholic steatohepatitis were described as
early as 1962 by the Honorary President of the Symposium, Professor
Herbert Thaler, from Vienna. Others followed, and in 1980 JA1/4rgen
Ludwig, one of the speakers of this symposium, introduced the name
non-alcoholic steatohepatitis' or NASH. In a Consensus Symposium
organized by the National Institute of Health (NIH) in Washington,
USA, in December 1998, NASH was recognized as one of the most
common liver diseases in Western countries when viral hepatitis and
heavy alcohol consumption were excluded. ASH, or alcoholic
steatohepatitis, is more common than NASH, since alcohol is
omnipresent in Western as well as Eastern cultures. Histologically
NASH and ASH are similar or even identical. Morphological findings
range from fatty degeneration to inflammation and fibrosis, and may
end up in liver cirrhosis. In spite of the well-defined
morphological features, our knowledge of epidemiology, aetiology,
and pathogenesis is full of gaps, especially for NASH. Therefore,
it is the purpose of this book to show the state of the art, to
discuss recent scientific data, and to suggest possible treatment
strategies, hoping to stimulate clinicians as well as scientists.
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