Worldwide investigations on mesenchymal stromal/stem cells (MSC)
have highlighted their regenerative potentials. Subsequent ex vivo
& in vivo studies, with or without biomaterial combination,
have explored MSC efficiency to repair damaged tissues and organs.
This book investigates some of key factors on MSC biology &
performance, such as the cell transportation procedures and the
vasculogenesis after transplantation. One of the prerequisites for
MSC introduction into clinic is their manipulation under good
manufacturing practice (GMP) facilities that are often far from the
operating theatre. Appropriate cell shipment conditions are poorly
defined, therefore in this book we describe the impact of
transportation on functional outcome focusing on bone regeneration.
We then focused on an innovative approach of adipose tissue
regeneration that reduced necrosis and significantly increased
vasculogenesis compared with common surgical procedure for adipose
tissue reconstruction based on autologous fat transfer. These data
may be useful for anyone who studies MSC looking for their
introduction into regenerative medicine approaches based on both
their differentiation and secretory potentials
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