The book entitled "Modern synthetic strategy for anti-viral
nucleosides" deals with the synthesis of four new series of
nucleosides, their characterization and antiviral screening.
Chemically, viruses are nucleoproteins containing either
deoxyribonucleic acid (DNA) or ribonucleic acid (RNA) surrounded by
a protective protein sheath. Nucleoside analogues are used as
anti-viral therapeutic agents. The development of antiviral drugs
encountered lots of difficulties and the research in antiviral
chemotherapy gained less attention. Although vaccination is a
valuable tool to fight viral diseases and in some cases is
available and successful, the difficulty associated with state-wide
or world-wide vaccination programs makes antiviral chemotherapy a
more practical approach in the fight to epidemic viral
infections.The importance of these nucleoside analogues was later
confirmed with the emergence of HIV as the main etiological agent
of AIDS. Due to growing awareness about environmental pollution,
library synthesis of target nucleosides by using green protocols is
desired. With this objective new nucleosides have been synthesized
using green protocol and screened for their antiviralactivity.
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