A puzzling epidemiological problem was the driving force behind the
discovery of human adenoviruses by Wallace Rowe and his colleagues
30 years ago. The de velopment of a plaque assay for poliomyelitis
virus in 1953 led us to the threshold of quantitative virology, and
in the same year the double-helical structure of DNA was discovered
and became a cornerstone of mo lecular biology. The potential of
adenoviruses as research tools in the molecular and cellular
biology of eukaryotic cells was recognized as early as the late
1950s and early 1960s by several investigators. Structural and
biochemical stu dies dominated the early years. In 1962, some of
the adenoviruses were the first human viruses shown to be oncogenic
in experimental animals. Thus adenovirology offered the
investigator the entire gamut of host cell interactions, productive
and abortive, as well as trans formed and tumor cell systems. The
possibilities that adenoviruses afforded for the study of the
molecular biology and genetics of eukaryotic cells were fully rea
lized in the late 1960s and the 1970s."
General
| Imprint: |
Springer-Verlag
|
| Country of origin: |
Germany |
| Series: |
Current Topics in Microbiology and Immunology, 109 |
| Release date: |
December 2011 |
| First published: |
1983 |
| Editors: |
W. Doerfler
|
| Dimensions: |
244 x 170 x 13mm (L x W x T) |
| Format: |
Paperback
|
| Pages: |
232 |
| Edition: |
Softcover reprint of the original 1st ed. 1983 |
| ISBN-13: |
978-3-642-69462-2 |
| Categories: |
Books >
Medicine >
Other branches of medicine >
Pathology >
Medical microbiology & virology
|
| LSN: |
3-642-69462-4 |
| Barcode: |
9783642694622 |
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