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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine

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Renin Angiotensin System and Cardiovascular Disease (Hardcover, 2010 ed.) Loot Price: R4,378
Discovery Miles 43 780
Renin Angiotensin System and Cardiovascular Disease (Hardcover, 2010 ed.): Walmor C.De Mello, Edward D. Frohlich

Renin Angiotensin System and Cardiovascular Disease (Hardcover, 2010 ed.)

Walmor C.De Mello, Edward D. Frohlich

Series: Contemporary Cardiology

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Loot Price R4,378 Discovery Miles 43 780 | Repayment Terms: R410 pm x 12*

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Experimental and clinical evidence supports the view that the activation of the renin angiotensin aldosterone system is involved in cardiovascular pathology including hypertension, heart failure, myocardial ischemia, and atherosclerosis. The present volume describes the intricacies involved in these processes, including the in?uence of prorenin/renin, angiotensin II, angiotensin (1-7), and aldosterone on cardiac and vascular functions as well as their involvement in the generation of cardiovascular diseases. Fundamental aspects like intracellular signaling, regulation of cell volume in the failing heart, and the presence of an intracrine renin angiotensin system are discussed. Moreover, the role of the mineralocorticoid receptor as an important c- ponent of the intracrine renin angiotensin system and as a regulator of extracellular action of angiotensin II is described, reinforcing the view that aldosterone inhibitors are helpful in the treatment of heart failure and hypertension. Let us hope the imp- tant topics included here motivate basic and clinical investigators and contribute to the development of new therapeutic approaches for cardiovascular diseases. We want to thank the distinguished authors and Humana Press for the opportunity to publish this important book. Walmor C. DeMello Edward Frohlich v Contents 1 Systemic Versus Local Renin Angiotensin Systems. An Overview ...1 Walmor C. DeMello and Richard N. Re 2 Clinical Import of the Local Renin Angiotensin Aldosterone Systems ...7 Edward D. Frohlich 3 Renin, Prorenin, and the (Pro)Renin Receptor ...15 Genevieve Nguyen and Aurelie Contrepas 4 Local Renin Angiotensin Systems in the Cardiovascular System ...25 Richard N.

General

Imprint: HumanaPress
Country of origin: United States
Series: Contemporary Cardiology
Release date: September 2009
First published: 2010
Editors: Walmor C.De Mello • Edward D. Frohlich
Dimensions: 235 x 155 x 21mm (L x W x T)
Format: Hardcover
Pages: 300
Edition: 2010 ed.
ISBN-13: 978-1-60761-185-1
Categories: Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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LSN: 1-60761-185-6
Barcode: 9781607611851

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