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Thrombolytic Therapy in Acute Ischemic Stroke (Paperback, 1991 ed.)
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Thrombolytic Therapy in Acute Ischemic Stroke (Paperback, 1991 ed.)
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During the last decade scientists in both basic and clinical
research have renew ed their interest in the potential role of
thrombolytic therapy in the treatment of acute ischemic stroke. The
reevaluation of this approach was kindled by our growing knowledge
of the pathogenesis of thrombotic and embolic stroke and by the
development of new thrombolytic agents. With no proven therapy for
acute ischemic stroke available, the potential value of early
pharmacologic recanalization of occluded vessels in the management
of acute stroke patients - an approach that has been supported by
animal experiments and a limited number of uncontrolled clinical
pilot studies - is again under scrutiny. A sym posium on
"Thrombolysis in Acute Cerebral Ischemia" was held in Heidel berg,
Germany, in May 1990 to summarize and discuss the
pathophysiological background for thrombolysis in acute ischemic
stroke and the recent ex perimental and clinical experience with
the new generation of thrombolytic agents. The editors are
fortunate to be able to include authoritative manuscripts from
almost all the speakers at the symposium. These include reports of
work by the most active investigators in this challenging field.
The editors wish to express their gratitude to all the contributors
for the additional work they have undertaken. Additionally, we
would like to thank Springer-Verlag, Heidelberg, for its generous
assistance in the preparation and rapid publication of this volume.
Heidelberg, August 1990 WERNER HACKE GREGORY J. DEL ZopPO MATTHIAS
HIRSCHBERG Contents I."
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