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Cell Cycle Checkpoints - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
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Cell Cycle Checkpoints - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2011)
Series: Methods in Molecular Biology, 782
Expected to ship within 10 - 15 working days
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Cell cycle checkpoints control the fidelity and orderly progression
of eukaryotic cell division. By controlling the orderly progression
of critical cell cycle events such as DNA replication and
chromosome segregation and ensuring proper repair of damaged DNA,
cell cycle checkpoints function to ensure genome integrity.
Mechanisms of checkpoint controls are not only the research focus
of investigators interested in mechanisms that regulate the cell
cycle, but are also the interests of researchers studying cancer
development as it is increasingly clear that loss of cell cycle
checkpoints, which leads to genomic instability as a result, is a
hallmark of tumorigenesis. Cell Cycle Checkpoints: Methods and
Protocols provides detailed descriptions of methodologies currently
employed by researchers in the field, including those commonly used
in the mammalian, yeast, C. elegans, Drosophila, and Xenopus model
systems. Each chapter describes a specific technique or protocol,
such as a method to induce cell cycle checkpoints in a particular
model system, to synchronize a population of cells to allow
observations of cell cycle progression, to identify genes involved
in checkpoint regulation, and to study particular protein
components of cell cycle checkpoint pathways. Written in the highly
successful Methods in Molecular Biology (TM) series format,
chapters contain introductions to their respective topics, lists of
the necessary materials and reagents, step-by-step, readily
reproducible laboratory protocols, and notes on troubleshooting and
avoiding known pitfalls. Authoritative and easily accessible, Cell
Cycle Checkpoints: Methods and Protocols seeks to serve both
professionals and novices with its well-honed methodologies in an
effort to further our knowledge of this essential field.
General
Imprint: |
HumanaPress
|
Country of origin: |
United States |
Series: |
Methods in Molecular Biology, 782 |
Release date: |
August 2016 |
First published: |
2011 |
Editors: |
Willis X. Li
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Dimensions: |
254 x 178mm (L x W) |
Format: |
Paperback
|
Pages: |
307 |
Edition: |
Softcover reprint of the original 1st ed. 2011 |
ISBN-13: |
978-1-4939-6181-8 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Cellular biology >
General
|
LSN: |
1-4939-6181-0 |
Barcode: |
9781493961818 |
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