Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Amlodipine (Paperback, 1993 ed.)
Loot Price: R2,958
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Amlodipine (Paperback, 1993 ed.)
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"Those who choose to increase their knowledge still further by
reading ... will discover an exciting new world. " NOEL WHITTAKER,
in "Making Money Made Simple" 1989. The development of calcium
antagonists has recently been described as representing "one of the
major advances in cardiovascular thera peutics of the latter half
of the twentieth century" (Braunwald, 1990). However, although the
development of these drugs started in the mid nineteen sixties it
is only recently that their real potential has begun to be
appreciated. Even now the calcium antagonist saga is not complete,
since new compounds continue to appear and new therapeutic applica
tions emerge. Based on the experience gained in the clinics in
which these drugs have been used recognition is being given now to
the need to improve upon the prototypes of the group. Such
improvement is resulting in the development and production not only
of long-acting formulations of the prototypes (nifedipine,
verapamil and diltiazem) but also of new calcium antagonists with
improved tissue selectivity, potency and duration of action. To
those of us who are interested in this field such a development is
both exciting and rewarding. As far as the clinicians who prescribe
these drugs are concerned the long-acting nature of some of the
newer calcium antagonists should make the satisfactory management
of their patients an achievable goal."
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