Leading neuroscience researchers offer a fresh perspective on
neuronal function by examining all its many components-including
their pertubation during major disease states-and relate each
element to neuronal demands. Topics range from the dependency of
neurons on metabolic supply, as well as on both ion and transmitter
homeostasis, to their close interaction with the myelin sheath.
Also addressed are the astrocytic signaling system that controls
synaptic transmission, the extracellular matrix and space as
communication systems, the role of blood flow regulation in
neuronal demand and in blood-brain barrier function, and
inflammation and the neuroimmune system. Insightful and
integrative, The Neuronal Environment: Brain Homeostasis in Health
and Disease demonstrates a clear new understanding that neurons do
not work in isolation, that they need constant interactions with
other brain components to process information, and that they are
not the only information processing system in the brain.
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