TGF- Signaling - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2016)

This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF- from the basic principles to the practical applications. Chapters provide basic introduction of TGF- signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF- signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Molecular Biology, 1344
Release date:	August 2016
First published:	2016
Editors:	Xin-Hua Feng • Pinglong Xu • Xia Lin
Dimensions:	254 x 178mm (L x W)
Format:	Paperback
Pages:	394
Edition:	Softcover reprint of the original 1st ed. 2016
ISBN-13:	978-1-4939-4993-9
Categories:	Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Promotions
LSN:	1-4939-4993-4
Barcode:	9781493949939

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