"Genomic Biomarkers for Pharmaceutical Development: Advancing
Personalized Health Care" provides an in-depth review of the state
of translational science across all stages of pharmaceutical
development with a special focus on personalized health care. This
book provides a complete picture of biomarker development and
validation in a pharmaceutical setting while addressing the
inherent challenges of targeting the appropriate indications,
biomarker robustness, regulatory hurdles, commercialization and
much more. It features case studies devoted to the applications of
pharmacogenomics, toxicogenomics, and other genetic technologies as
they support drug discovery and development.
With chapters written by international authorities in industry
and academia, this work is a truly unique presentation of the
thoughts and approaches that lead to the development of
personalized medicine. Intended for all those involved in clinical
translational research, this book is the ideal resource for
scientists searching for the applications, strategies and
successful approaches of translational science in pharmaceutical
development.
Provides case studies in applications of pharmacodynamic and
predictive markers in drug development in oncology, autoimmunity,
respiratory diseases and infectious diseasesShows how to identify
potential new therapeutic targets in different diseases and
provides examples of potential new disease indications for life
cycle management of drugsAuthored by leading international experts
from industry and academia
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