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Cancer Targeted Drug Delivery - An Elusive Dream (Hardcover, 2013 ed.)
Loot Price: R6,515
Discovery Miles 65 150
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Cancer Targeted Drug Delivery - An Elusive Dream (Hardcover, 2013 ed.)
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This book was conceived from a simple question as to why cancer is
so difficult to treat. Ultimately we want to find ways to cure
cancers, but that may be an elusive dream at least with the
technologies we have now and expect to have in the near future.
This leads the question of whether it is possible to improve
current cancer treatment methods, especially from the perspective
of enhancing targeted drug delivery to tumors. This volume is
designed to provide information related to the difficulties in
treating cancers through targeted drug delivery, our current
understanding of cancer biology, and potential technologies that
might be used to achieve enhanced drug delivery to tumors. An ideal
drug delivery system for treating cancers would maximize the
therapeutic efficacy with minimal side effects in clinical
applications. The seemingly improved anticancer efficacy of the
current nanoparticle-based formulations needs to be viewed from the
context of very poor success rates for translation to human
applications. The results of in vitro cell culture models and small
animal in vivo experiments have not been extrapolated to clinical
applications. Finding the reasons for the lack of successful
translation is required if we are to discover approaches to
substantially extend the survival time of cancer patients, and
hopefully identify cures. Cancer Targeted Drug Delivery: Elusive
Dream describes some answers of achieving the so far elusive dream
of treating cancers like other chronic diseases with therapies that
focus using improved drug delivery systems designed to better align
with the unique biological and physiological properties of cancer.
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