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RNA Imaging - Methods and Protocols (Hardcover, 1st ed. 2016)
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RNA Imaging - Methods and Protocols (Hardcover, 1st ed. 2016)
Series: Methods in Molecular Biology, 1372
Expected to ship within 12 - 17 working days
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This detailed volume will focus on the phenomenon of RNA
interference by providing comprehensive coverage of various
techniques for in vivo micro/siRNA imaging including the design and
synthesis of specific imaging agents and tools, the development of
imaging methodologies, and their interpretation. An essential
element in the development and optimization of these therapies is
the ability to measure the bioavailability and functionality of the
RNA/oligonucleotide molecule after administration into the body.
Noninvasive imaging provides the necessary set of tools to
accomplish this in authentic physiologic environments and across
time. Written for the highly successful Methods in Molecular
Biology series, chapters include introductions to their respective
topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Authoritative and
practical, RNA Imaging: Methods and Protocols serves physicians,
scientists, and graduate students who are either new to the field
of RNA-based imaging and its associated therapeutic applications or
who wish to be apprised of recent advances in the state of the art.
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