The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.
Goes beyond the standard engineering issues covered by most books and delves into structure-function relationshipsIntegration of knowledge across all areas of antibody engineering, development, and marketingDiscusses how current and future genetic engineering of cell lines will pave the way for much higher productivity

Principles of Market Abuse Regulation: A Comparative South African Perspective arguably offers the most comprehensive study of the regulation and enforcement of anti-market abuse laws in South Africa today. Accordingly, the book examines the regulation of the South African securities and financial markets to identify the strengths and weaknesses of the country's anti-market abuse laws. In this regard, the book provides that inadequate and inconsistent regulation of the securities and financial markets could give rise to low investor confidence, market volatility and poor market integrity. The author traces the regulation of market abuse under the Financial Markets Act 19 of 2012 and recommends measures that could enhance the combating of market abuse in the South African securities and financial markets. The Financial Sector Regulation Act 9 of 2017, which is set to expand the mandate of the Financial Services Board, is also considered. The global financial crisis of 2007-2009 provides context for the book. Events covered include South African and American international banks' collusion and market manipulation involving price-fixing, market allocation and rigging in the trading of foreign currency pairs of the South African rand since 2007.

Granting Justice takes issue with the characterisation of the South African state as “developmental”. The crucial aspect of care is missing from the practice for this to be the case. Thus, while the grants address the immediate survival needs of many South Africans, social justice requires quite a different approach, an approach of care that would grant agency and dignity to recipients.

Tessa Hochfeld adopts a highly personal narrative style of writing that reflects the ethical standpoint that she took during her research. Telling a story is what makes her writing so strong and distinguishes it in the development literature.

The book falls into the fields of development studies, and social welfare and social development. The following are possible keywords: social justice; gender justice; care; social development; poverty; social protection; southern welfare; family strengthening; developmental social work.

Noah Baumbach writes and directs this comedy starring Ben Stiller and Naomi Watts as a childless married couple living in New York who befriend a younger and more exciting couple. Fed up of their friends who pressure them into beginning a family of their own, documentary film-maker Josh (Stiller) and wife Cornelia (Watts) meet hipster couple Jamie (Adam Driver) and Darby (Amanda Seyfried) and start to enjoy the new and refreshing experiences that come with the territory. However, are Jamie and Darby's motivations for spending time with the older couple as harmless as they seem?

Take a refreshing walk through the woods without even leaving your home. Woodlands are everyone’s favourite landscapes and, from a colouring perspective, they’re full of amazing details. Acorns, bluebells, curling ferns, toadstools and leaves all give the colourist a calming, natural and satisfying experience. Meander through this uplifting woodland journey of meditative scenes and be inspired by uplifting quotations gently scattered through the pages.

This cutting-edge Handbook argues for social protection to be situated in a wider system of social welfare and development programmes for low- and middle-income countries. Focusing on the role of citizens and communities in enhancing human development, it explores how welfare systems are unfolding in diverse contexts across the global South. Tracing the evolution and theory of social protection, the Handbook examines the nature, design, scope, goals and linkages of social protection and social development programmes. Case studies examine responses to the COVID-19 pandemic; the entrepreneurial character of modern social protection schemes; cash transfer schemes and the move towards cash-plus policies; and the fluidity between progression and regression of social protection. With global and regional reviews of social protection from in-country experts, the Handbook provides innovative solutions to key challenges. Bridging theoretical and empirical approaches, the Handbook on Social Protection and Social Development in the Global South will prove an invaluable resource for academics and graduate students of development, social policy and sociology. Its comprehensive overview of the field will also be useful for policymakers and practitioners working on social welfare and development in the global South.

Handy reference that is as fast and durable as those people who choose to work in the world of mass media. Every tool helps with today's challenging goal of sharing information that is accurate, precise, clear and without bias, online, on air or in print (in words, photos, videos, or graphics, and in many mediums). The info you need to know regarding principles and guidelines to ethics, types of writing, uses of photography and videography, terminology, style, spelling, punctuation, and grammar is here in 6 laminated pages designed for quick access. Students in communications, mass media, and journalism, experienced writers, editors, managers and others at magazines, newspapers and news bureaus will find this tool a must-have. AP is also used in business for writing press releases, marketing campaigns and other corporate items, as well as online-only publishers, web content creators and bloggers. 6 page laminated guide includes: What Is AP Style? Special AP Stylebook Sections Broadcast Guidelines Business Guidelines Data Journalism Food Guidelines AP Principles Accuracy in Images Aim for On-the-Record Reporting Avoid Hate Speech Conflicts of Interest Copyright Infringement Corrections Data & Graphics Privacy Responses Social Media Terminology Punctuation Other Styles Recent Updates

An exquisite collection presenting 100 Persian home-cooking recipes and stories from one family collection

When Leila Heller's mother, Nahid Taghinia-Milani came to the United States in 1979, she brought her recipes with her. Persian Feasts features Iranian delicacies in a dazzling tapestry of textures and aromas, from Shiraz in the south to Tabriz in the north.

This exquisite collection of 100 dishes includes hearty stews, saffron-infused rice dishes, succulent kebabs, and delicate rosewater desserts – each one telling a story that is steeped in tradition and has been passed down from generation to generation. Unexpected ingredient combinations create distinctive tastes and aromas to every dish – from a simple Herb Frittata to a comforting Eggplant, Walnut & Pomegranate Stew to a delicately perfumed Cardamom and Rose Water Pudding.

This highly personal book for home cooks – including family stories, historical accounts of food culture, recipe origins, and celebratory menus – is a feast for the senses, celebrating an abundance of spectacular food prepared with seasonal ingredients, fresh herbs, and fragrant spices. Beautiful specially commissioned food photography captures the bounty of this vibrant cuisine.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

3rd Generation Biofuels: Disruptive Technologies to Enable Commercial Production is a comprehensive volume on all aspects of algal biofuels, offering the latest advances on commercial implementation. In addition to the fundamentals, the book discusses all applied aspects of 3rd generation biofuels production, including design approaches, unit operations of the upstream and downstream biomass processing, and every potential microalgae-based energy product, including microbial fuel cells. Policy, economic, environmental, and regulatory issues are addressed in a dedicated section. Finally, the book presents pilot and demonstration-scale projects for 3rd generation biofuels production in the format of a white paper. Each chapter reviews the state of the art, discusses the disruptive technological approaches that will potentially enable large-scale production, and concludes with specific recommendations on how to achieve commercial competitiveness. The book provides readers with an invaluable reference for researchers, graduates, and practitioners working in the areas of renewable energy, bioenergy and alternative fuels, and biotechnology.

Sustainability Metrics and Indicators of Environmental Impact: Industrial and Agricultural Life Cycle Assessment covers trending topics on the environmental impact of systems of production, putting emphasis on lifecycle assessment (LCA). This methodology is one of the most important tools of analysis, as mathematical models are applied that will quantify the systematic inputs and outputs of the processes in order to evaluate the sustainability of industrial processes and products. In this sense, LCA is mainly a tool to support environmental decision-making that analyzes the environmental impacts of products and technologies from a lifecycle perspective. The emergence of ever-larger global issues, such as the energy dilemma, the changing climate and the scarcity of natural resources, such as water, has boosted the search for tools capable of ensuring the reliability of the results published by the industries, and has become an important tool in order to achieve sustainability and environmental preservation. Thus, lifecycle assessment (LCA), including carbon footprint valuation is necessary to ensure better internal management.

Handbook of Food and Feed from Microalgae: Production, Application, Regulation, and Sustainability is a comprehensive resource on all aspects of using microalgae in food and feed. This book covers applied processes, including compounds found in microalgae applicable in food and feed, food products developed with microalgae biomass in the composition, the use of microalgae in animal nutrition, and challenges and recent advances. Written by global leading experts on microalgae, the book's sections discuss the fundamentals of food and feed from microalgae, including its biodiversity, biogeography, genomics, nutritional purposes and compounds found within microalgae like proteins, vitamins and antioxidants. In addition, the book explains the incorporation of microalgae into meat, dairy, beverages and wheat products, as well as in real-world food applications in aquaculture, mollusk, poultry and pet feeding. The last two sections cover challenges and issues such as bioavailability and bio-accessibility and how to address safety, regulatory, market, economics and environment concerns.