From one of tech's boldest thinkers and his longtime deputy, this is a sweeping indictment of Silicon Valley and treatise on how the West has slid into a culture of complacency - even as we enter a new era of mounting global threats.

Once upon a time, the most brilliant engineering minds once collaborated with government to advance world-changing technologies. Their efforts secured the West's dominance and kept its people safe. Now, our relationship with new technologies has become shallow-and the repercussions could not be more perilous.

Today, engineers and founders build photo-sharing apps and marketing algorithms, furthering the ambitions of whoever can exploit them. This complacency has spread into academia, politics, and the boardroom. The result? An entire generation for whom the narrow-minded pursuit of the whims of a late capitalist economy has become their calling.

In this groundbreaking treatise, one of tech's boldest thinkers and his longtime deputy offer a searing critique of our collective abandonment of ambition. Palantir co-founder and CEO Alexander C. Karp and Nicholas W. Zamiska argue that in order for the West to retain its global edge-and preserve the freedoms we take for granted-the software industry must renew its commitment to addressing our most urgent challenges, including the new arms race of artificial intelligence. Governmen , in turn, must embrace the most effective features of the engineering mindset that have propelled Silicon Valley's success.

Above all, leaders must reject intellectual fragility and preserve space for ideological confrontation. A willingness to risk the disapproval of the crowd, Karp and Zamiska contend, has everything to do with technological and economic outperformance.

At once iconoclastic and rigorous, this book will also lift the veil on Palantir and its broader political project from the inside, offering a passionate call for the West to wake up to our new reality.

Nu Metal: Resurgence documents the groundbreaking movement from its original inception, right up to the present day. Featuring fully detailed band biographies that includes major players such as Korn, Limp Bizkit, Linkin Park, Papa Roach, Rammstein and Slipknot, a guide to 'The Nu Breed' of bands coming up like Cane Hill, DED, Frontstreet and Lethal Injektion, and exclusive interviews with members of classic Nu Metal bands that includes Alien Ant Farm, Coal Chamber, Kittie, Nonpoint, Orgy, Spineshank and Taproot; as well as record producer extraordinaire Ross Robinson- Nu Metal: Resurgence confirms once and for all that Nu Metal is indeed here to stay.

Hybrid Rocket Propulsion Design Handbook provides system scaling laws, design methodologies, and a summary of available test data, giving engineers all the tools they need to develop realistic hybrid system designs.Important supporting theory from chemistry, thermodynamics, and rocket propulsion is addressed, helping readers from a variety of backgrounds to understand this interdisciplinary subject. This book also suggests guidelines for standardized reporting of test data, in response to difficulties researchers have in working with results from different research institutes.

"Micro- and Nanoengineering of the Cell Surface"explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis.

The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas.
Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypesProvides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surfaceUnlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics"

This issue of PET Clinics focuses on Total Body PET Imaging, and is edited by Drs. Lorenzo Nardo, Ramsey Badawi, Joel S. Karp and Austin Pantel. Articles will include: UC Davis update on the uEXPLORER; Zhongshan update on the uEXPLORER; UPenn update on the PennPET Explorer; Total body imaging instrumentation design considerations; 3D/4D reconstruction and quantitative total body imaging; Analysis of 4D data for total body imaging; Total body imaging and cancer; Total body imaging and metabolic disease; Total body imaging and infection; Total body imaging and musculoskeletal disease; Total body imaging and cardiovascular disease; Total body imaging and cardiac applications; Total body imaging and neuroimaging; and more!

Biology and Engineering of Stem Cell Niches covers a wide spectrum of research and current knowledge on embryonic and adult stem cell niches, focusing on the understanding of stem cell niche molecules and signaling mechanisms, including cell-cell/cell-matrix interactions. The book comprehensively reviews factors regulating stem cell behavior and the corresponding approaches for understanding the subsequent effect of providing the proper matrix molecules, mechanical cues, and/or chemical cues. It encompasses a variety of tools and techniques for developing biomaterials-based methods to model synthetic stem cell niches in vivo, or to enhance and direct stem cell fate in vitro. A final section of the book discusses stem cell niche bioengineering strategies and current advances in each tissue type.

This is the first comprehensive International Handbook on the History of Mathematics Education, covering a wide spectrum of epochs and civilizations, countries and cultures. Until now, much of the research into the rich and varied history of mathematics education has remained inaccessible to the vast majority of scholars, not least because it has been written in the language, and for readers, of an individual country. And yet a historical overview, however brief, has become an indispensable element of nearly every dissertation and scholarly article. This handbook provides, for the first time, a comprehensive and systematic aid for researchers around the world in finding the information they need about historical developments in mathematics education, not only in their own countries, but globally as well. Although written primarily for mathematics educators, this handbook will also be of interest to researchers of the history of education in general, as well as specialists in cultural and even social history.

This third edition of a classic urban sociology text examines critical but often-neglected aspects of urban life from a social-psychological theoretical perspective. Symbolic interaction is among the most central theoretical paradigms in sociology and the theory that most thoroughly attends to how individuals give meaning to their world-in this case, how city dwellers interpret and respond to their daily experiences as urbanites. This thoroughly updated edition of Being Urban: A Sociology of City Life remains true to this particular theoretical angle of vision-the symbolic interactionist approach-focusing on specific topics that are relatively neglected in other urban sociology texts, and that lend themselves to the kind of social-psychological analyses that define the distinctive conceptual core of the authors' efforts. After the first two chapters supply readers with theoretical foundations of urban sociology, the next four chapters describe the various ways that individuals experience and make sense of key aspects of urban life. The final section-also composed of four chapters-addresses strategically chosen urban institutions and related processes of social change. Specific subject areas covered include sports, everyday public life, tolerance for diversity, women in cities, urban politics, and the arts. Readers will learn about how order is maintained in public urban places, understand why cities naturally breed a tolerance for diversity that may not be so easily achieved in less urban settings, and appreciate the delicate political and economic tensions between cities and their surrounding suburbs. Provides a complete analysis of the important social psychological dimensions of urban life that are often overlooked Supplies a comprehensive description of the 19th-century theoretical roots of urban sociology Enables readers to see concretely how theories are "applied" to illuminate the operation of a range of urban cultures, processes, and structures Considers a number of topics that are likely to resonate with readers personally, such as alternative approaches to the concept of "community," the daily organization of city life, and the phenomenon of urban tolerance of diversity Includes an up-to-date, new chapter on the arts and urban life

World War I utterly transformed the lives of Jews around the world: it allowed them to display their patriotism, to dispel antisemitic myths about Jewish cowardice, and to fight for Jewish rights. Yet Jews also suffered as refugees and deportees, at times catastrophically. And in the aftermath of the war, the replacement of the Habsburg Monarchy and the Russian and Ottoman Empires with a system of nation-states confronted Jews with a new set of challenges. This book provides a fascinating survey of the ways in which Jewish communities participated in and were changed by the Great War, focusing on the dramatic circumstances they faced in Europe, North America, and the Middle East during and after the conflict.

When we were first approached by Dr. Lucky to write this book we were very enthusiastic about the prospect, since we had contemplated a similar project for quite some time. The difficulty lay in how best to digest the vast amount of data on optical propagation, reduce it to a book of manageable size, and simultaneously form the transition from the physics of propagation to the engineering of optical channels. This is the intent of Optical Channels. In accomplishing our goal it was necessary to condense the material on optical propagation and, in so doing, we have left a large amount to be handled via references. We have tried to make these decisions in a consistent manner so that the book will be uniform in its treatment of this topic. We identify four channels for consideration: the free-space channel, which: is characteristic of a tranquil atmosphere or a space-to-space link; the turbulent channel, which is characteristic of the atmospheric channel; the scatter channel in two forms, clouds and water; and the fiber optic channel. For each of these channels we have tried to reduce the applicable propagation theory to a level that can be used for engineering design. This has been done by example, but here again decisions had to be made on which examples to present. We have not tried to present any material on optical components and consequently other references on engineering would be necessary to supplement this book.

The experience and knowledge acquired in teacher education courses should build important fundamentals for the future teaching of mathematics. In particular, experience in mathematical problem solving, and in planning lessons devoted to problem solving, is an essential component of teacher preparation. This book develops a problem solving approach and is intended to be a text used in mathematics education courses (or professional development) for pre-service or in-service middle and secondary school teachers. It can be used both in graduate and undergraduate courses, in accordance with the focus of teacher preparation programs. The content of the book is suited especially for those students who are further along in their mathematics education preparation, as the text is more involved with mathematical ideas and problem solving, and discusses some of the intricate pedagogical considerations that arise in teaching. The text is written not as an introduction to mathematics education (a first course), but rather as a second, or probably, third course. The book deals both with general methodology issues in mathematics education incorporating a problem solving approach (Chapters 1-6) and with more concrete applications within the context of specific topics - algebra, geometry, and discrete mathematics (Chapters 7-13). The book provides opportunities for teachers to engage in authentic mathematical thinking. The mathematical ideas under consideration build on specific middle and secondary school content while simultaneously pushing the teacher to consider more advanced topics, as well as various connections across mathematical domains. The book strives to preserve the spirit of discussion, and at times even argument, typical of collaborative work on a lesson plan. Based on the accumulated experience of work with future and current teachers, the book assumes that students have some background in lesson planning, and extends their thinking further. Specifically, this book aims to provide a discussion of how a lesson plan is constructed, including the ways in which problems are selected or invented, rather than the compilation of prepared lesson plans. This approach reflects the authors' view that the process of searching for an answer is often more important than the formal result.

This edited book by Mills and Karp brings together political, legal and moral perspectives on the responsibilities of human rights protection in world politics today. It critiques a narrow focus on states' 'violations' of human rights, incorporates non-state actors, and looks beyond the 'Responsibility to Protect' policy framework.

President William McKinley's image is thought of as a weak, ineffectual man who did not want to get involved in a war with Spain but was forced into it by events beyond his control. The truth--as laid out in Walter Karp's The Politics of War--is quite different. The Spanish-American War--or, more rightly, Massacre or Rout was a manufactured crisis. The parallels are inescapable. War is led by the rich and powerful often against the wishes of the public. While the war strengthened the System for the moment, public hostility to the political and economic status quo began to rise against the ruling parties. What followed was one of the bloodiest centuries mankind has seen. We can only hope that history does not repeat itself.

Designed for quick, everyday reference, Handbook of Targeted Cancer Therapy and Immunotherapy, 3rd Edition, includes clinical trial results of more than 250 state-of-the-art targeted therapy and immunotherapy agents, providing a practical, intuitive, colorful overview of this rapidly advancing field. Comprehensive yet concise, this easy-access resource by Drs. Daniel D. Karp, Gerald S. Falchook, and JoAnn D. Lim, helps you navigate through the newest research reports and apply the most recent discoveries as they pertain to specific tumor types, actionable molecular targets, and clinical performance of investigational targeted agents and combinations of agents. This handbook presents information distilled by dozens of translational research clinicians and other healthcare experts with hundreds of years of cumulative experience in the revolutionary area of genomically based precision oncology. Covers cancer targets-phase 1, 2, and 3 trials and preliminary results, as well as approved therapies. Includes sections on Molecular Targets and Pathways, and Targeted and Immunotherapy Agents. Contains a section on Carcinogenesis from the Perspective of Targeted Therapy and Immunotherapy, with essential content on biology, immunology, and immunotherapy. Organizes information by tumor type, pathway, and drug name, so you can approach clinical challenges from any direction. Highlights FDA approvals throughout. Pocket-sized and color coded to help you find information quickly and easily. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

The book is a collection of problems in school mathematics specifically written for the teachers. It is an attempt to enrich prospective and current teachers with the deep knowledge of school mathematics and to develop their reasoning and proving skills. Also, it is supposed to help them to anticipate and analyze their students' errors and use them as teachable moments. The book is intended to be used in mathematics education courses (or professional development) for pre-service or in-service secondary school teachers. It can be used in graduate and undergraduate courses, in accordance with the orientations of different teacher preparation programs. Additionally, it can be used for the independent studies. One can also imagine situations in which teachers might use certain problems from this problem book directly in working with students, but this would constitute a supplementary use of the book.

This book is a collection of scholarly studies in the history of mathematics education, very abbreviated versions of which were presented at the ICMI Congress in 2021. The book discusses issues in education in Brazil and Belgium, in Poland and Spain, in Russia and the United States. Probably the main factor that unifies the chapters of the book is their attention to key moments in the formation of the field of mathematics education. Topics discussed in the book include the formation and development of mathematics education for women; the role of the research mathematician in the formation of standards for writing textbooks; the formation of curricula and the most active figures in this formation during the New Math period; the formation of certain distinctive features of curricula in Poland; the formation of the views of David Eugene Smith and the influence of European mathematics education on him; the formation of the American mathematics community; and the creation of such forms of student assessment as entrance exams to higher educational institutions. The book is of interest not only to historians of mathematics education, but also to wide segments of specialists in other areas of mathematics education.

ICMI (or IMUK) was founded in 1908 and initiated the establishment of national subcommissions to launch national activities in response to the IMUK agenda and to promote the reform proposals within each member country.While ICMI's activities were thoroughly studied, the activities of the national subcommissions are studied only very marginally. In the meantime, their work has been of major importance - both because of their role in exploring and documenting the development of mathematics education at the beginning of the 20th century, and because of the changes and new ideas which they brought to their countries. Importantly, even if some results of their activities were analyzed within their countries in the corresponding languages, almost nothing is known internationally. This book is planned to deepen our knowledge on at least some of the national subcommissions. The book will interest both researchers and others interested in mathematics education and its development.