Having last year published "Up from Clinical Epidemiology &
EBM" and also "Epidemiological Research: Terms and Concepts,"
Miettinen now - this time with collaboration from his junior
colleague I. Karp - brings out this further introduction into
epidemiological research; and he is now working on an introduction
into clinical research, for publication next year. It evidently is
Miettinen's felt time to crystallize the basic understandings he
has come to as the culmination of a half-century of concentrated
effort to advance the theory of epidemiological and
'meta-epidemiological clinical' research.
In accord with its title, this book focuses on research to
develop the knowledge-base for preventive medicine, which mainly is
knowledge about the causal origin -etilogy, etiogenesis - of
illness. It first illustrates how wanting this knowledge still is,
despite much research; and it then aims to guide the reader to more
productive etiogenetic research.
This book places much emphasis on the need to assure relevance
by principles-guided objects design for the studies, which now
remains conspicuously absent from epidemiologists' concerns. And as
for methods design, this book exposes the fallacies in the
still-common 'cohort' and 'case-control' studies, defines the
essentials of all etiogenetic studies, and then addresses the true
options for design in this framework of shared essentials.
A good deal of attention is also given to the still
commonly-held, very major, twin fallacies that screening for an
illness is a preventive intervention, to be studied by randomized
trials, and that research on it can imply rational guidelines or
recommendations regarding decisions about the screening.
While Miettinen already is regarded as 'the father of modern
epidemiology, ' he now appears to have become the father also of
post-modern epidemiology, where 'epidemiology' still means
epidemiological research."
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