This volume looks at the latest advancements in imaging neuroscience methods using magnetic resonance imaging (MRI) and electroencephalography (EEG) to study the healthy and diseased brain. The chapters in this book are organized into five parts. Parts One and Two cover an introduction to this field and the latest use of molecular models. Part Three explores neurophysiological methods for assessment, such as quantitative EEG and event-related potentials. Part Four discusses the advances and innovations made in computational anatomy, and Part Five addresses the challenges faced by researchers prior to the computational neuroscience to find wider translational applications in the field of psychiatry and mental health. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.  Cutting-edge and comprehensive, Computational Neuroscience is a valuable tool for researchers in the psychiatry and mental health fields who want to learn more about ways to incorporate computational approaches into utility and validity of clinical methods.

This book covers the method of metric distances and its application in probability theory and other fields. The method is fundamental in the study of limit theorems and generally in assessing the quality of approximations to a given probabilistic model. The method of metric distances is developed to study stability problems and reduces to the selection of an ideal or the most appropriate metric for the problem under consideration and a comparison of probability metrics. After describing the basic structure of probability metrics and providing an analysis of the topologies in the space of probability measures generated by different types of probability metrics, the authors study stability problems by providing a characterization of the ideal metrics for a given problem and investigating the main relationships between different types of probability metrics. The presentation is provided in a general form, although specific cases are considered as they arise in the process of finding supplementary bounds or in applications to important special cases. Svetlozar T. Rachev is the Frey Family Foundation Chair of Quantitative Finance, Department of Applied Mathematics and Statistics, SUNY-Stony Brook and Chief Scientist of Finanlytica, USA. Lev B. Klebanov is a Professor in the Department of Probability and Mathematical Statistics, Charles University, Prague, Czech Republic. Stoyan V. Stoyanov is a Professor at EDHEC Business School and Head of Research, EDHEC-Risk Institute-Asia (Singapore). Frank J. Fabozzi is a Professor at EDHEC Business School. (USA)

Dedicated to the Russian mathematician Albert Shiryaev on his 70th birthday, this is a collection of papers written by his former students, co-authors and colleagues. The book represents the modern state of art of a quickly maturing theory and will be an essential source and reading for researchers in this area. Diversity of topics and comprehensive style of the papers make the book attractive for PhD students and young researchers.

The book deals with the theory and practice of all electrophoretic steps leading to proteome analysis, i.e. isoelectric focusing (including immobilized pH gradients), sodium dodecyl sulphate electrophoresis (SADS-PAGE) and finally two-dimensional maps. It is a reasoned collection of all modern, relevant, up-to-date methodologies leading to successful fractionation, analysis and characterization of every polypeptide spot in 2-D map analysis. It includes chapters on the most sophisticated mass spectrometry developments and it helps the reader in navigating through the most important databases in proteome analysis, including step by step tours in selected sites. Yet, this book's unique strength and feature is the fact that it combines not only practice (in common with any other book on this topic) but also theory, by giving a detailed treatment on the most advanced theoretical treatments of steady-state techniques, such as isoelectric focusing and immobilized pH gradients. A lot of this theory is newly developed and presented to the public for the first time. Thus, this book should satisfy not only the needs of every day practitioners, but also the desires of the most advanced theoreticians in the field, who will surely appreciate the novel theories presented here.
Also the methodological section contains several as yet unpublished protocols, correcting some of the existing ones and showing the pitfall and limitations of even well ingrained protocols in proteome analysis, which are here critically re-evaluated for the first time.

For historical and socio-economic reasons, the countries of the southern Black Sea region are facing mounting and apparently intractable problems in managing their solid waste, with increasingly serious implications for public health and quality of life, as well as the wider socio-economic development of the region. Hitherto, no comprehensive, systematic study of the problem seems to have been conducted, to determine the underlying causes and suggesting how it might be alleviated in socially and economically viable ways, aiming at sustainability. The present book analyzes the causes of the poor state of solid waste management in the region, identifying feasible modalities with which at least a degree of sustainability could be achieved in the management of the region's solid waste. Readership: Environmental managers, scientists, planners, policy makers, technical and investment consultants, businesses and other enterprises and institutions concerned with sustainable solid waste management in the region.

Approach your problems from the right end It isn't that they can't see the solution. It is and begin with the answers. Then one day, that they can't see the problem. perhaps you will find the final question. G. K. Chesterton. The Scandal of Father 'The Hermit Clad in Crane Feathers' in R. Brown 'The point of a Pin'. van Gulik's The Chinese Maze Murders. Growing specialization and diversification have brought a host of monographs and textbooks on increasingly specialized topics. However, the "tree" of knowledge of mathematics and related fields does not grow only by putting forth new branches. It also happens, quite often in fact, that branches which were thought to be completely disparate are suddenly seen to be related. Further, the kind and level of sophistication of mathematics applied in various sciences has changed drastically in recent years: measure theory is used (non-trivially) in regional and theoretical economics; algebraic geometry interacts with physics; the Minkowsky lemma, coding theory and the structure of water meet one another in packing and covering theory; quantum fields, crystal defects and mathematical programming profit from homotopy theory; Lie algebras are relevant to filtering; and prediction and electrical engineering can use Stein spaces. And in addition to this there are such new emerging subdisciplines as "experimental mathematics," "CFD," "completely integrable systems," "chaos, synergetics and large-scale order," which are almost impossible to fit into the existing classification schemes. They draw upon widely different sections of mathematics.

The field of academic psychiatry is in crisis, everywhere. It is not merely a health crisis of resource scarcity or distribution, competing claims and practice models, or level of development from one country to another, but a deeper, more fundamental crisis about the very definition and the theoretical basis of psychiatry. The kinds of questions that represent this crisis include whether psychiatry is a social science (like psychology or anthropology), whether it is better understood as part of the humanities (like philosophy, history, and literature), or if the future of psychiatry is best assured as a branch of medicine (based on genetics and neuroscience)? In fact, the question often debated since the beginning of modern psychiatry concerns the biomedical model so that part of psychiatry's perpetual self-questioning is to what extent it is or is not a branch of medicine. This unique and bold volume offers a representative and critical survey of the history of modern psychiatry with deeply informed transdisciplinary readings of the literature and practices of the field by two professors of psychiatry who are active in practice and engaged in research and have dual training in scientific psychiatry and philosophy. In alternating chapters presenting contrasting arguments for the future of psychiatry, the two authors conclude with a dialogue between them to flesh out the theoretical, research, and practical implications of psychiatry's current crisis, outlining areas of divergence, consensus, and fruitful collaborations to revision psychiatry today. The volume is scrupulously documented but written in accessible language with capsule summaries of key areas of theory, research, and practice for the student and practitioner alike in the social and human sciences and in medicine, psychiatry, and the neurosciences.

This book presents the analysis of up-to-date techniques used for the determination of acid-base properties in view of their applicability to examination of solid organic and inorganic surfaces. The studies have been carried out by the authors since 1993, showing experimental data on surface properties of more than 150 polymers, such as carbocatenary and heterochain polymers, copolymers and their blends, as well as different epoxy and rubber compositions used in adhesive joints. The adhesive ability of metal-polymer systems based on epoxy compositions, polyolefins, and rubbers was studied as a function of absolute difference in acid-base properties of adhesive and adherends, and the possibility to predict adhesive interaction on this basis was experimentally verified. The book shows the important role that acid-base interactions play in establishing interfacial adhesive-adherent contact and outlines practical recommendations regarding parameters of quantitative estimation of acid-base surface properties that implies the relationship with adhesive ability in polymer-metal systems. Creating polymeric materials with greater strength characteristics when in contact with metals is the most important problem when adhesive joints are designed. The authors obtained experimental data for thermodynamic and acid-base properties of about 200 organic and inorganic surfaces that find a wide practical application. These results may be used as a reference source to predict the adhesive ability of different coating systems. The possibility to predict adhesive interaction of adhesive with adherend, taking into account the absolute difference in their acidity and basicity, was verified experimentally.

Technical and technological development demands the creation of new materials that are stronger, more reliable, and more durable-materials with new properties. This new book covers a broad range of polymeric materials and technology and provides researchers in polymer science and technology with new research on the functional materials production chain. Chapters in this new volume highlight recent developments in advanced polymeric materials from macro- to nano-length scales. Composites are becoming more important because they can help to improve quality of life. This volume presents the latest developments and trends in advanced polymer materials and structures. It discusses the developments of advanced polymers and respective tools to characterize and predict the material properties and behavior. This book has an important role in advancing polymer materials in macro and nanoscale. Its aim is to provide original, theoretical, and important experimental results that use non-routine methodologies. It also includes chapters on novel applications of more familiar experimental techniques and analyses of composite problems that indicate the need for new experimental approaches.

This book reports on new methodologies and important applications in the field of nanopolymers as well as includes the latest coverage of chemical databases and the development of new computational methods and efficient algorithms for chemical software and chemical engineering. The book provides an overview of the field, explains the basic underlying theory, and gives numerous comparisons of different methods. The new topics covered in this book will be an excellent resource for industries and academic researchers as well.

With chapters by the editors and other experts in the field of polymer science, this book covers a broad selection of important research advances in the field, including updates on enzymatic destruction and photoelectric characteristics, studies on the changes in the polymer molecular mass during hydrolysis and a new type of bioadditive for motor fuel, and an exploration of the interrelation of viscoelastic and electromagnetic properties of densely cross-linked polymers. Also included are chapters that discuss the problems of mechanics of textile performance, new aspects of polymeric nanofibers, a mathematical model of nanofragment cross-linked polymers, and much more.

Ikujiro Nonaka’s A Dynamic Theory of Organisational Knowledge Creation outlines the creation of organisational knowledge through the constant conversion of the two types of knowledge, tacit and explicit, which Nonaka believes has the potential to guide managers’ knowledge creation strategies. This argument is centred on the conviction that companies are not passive parties that simply utilise existing knowledge for providing solutions to the customers, and that organisations and environments simultaneously influence knowledge creation. This text is considered fundamental for the knowledge management field and as such, it has been utilised by a large number of academics.

Argyris’s Integrating The Individual and the Organization is part of a series of essays and books considering how organisations should be run. This essay explores the lack of congruence between the needs and expectations of individual employees and the organisations that employ them. Grounding his argument in studies on human nature, Argyris highlights that demands of greater independence, an expansion of interests, and re-orientation of goals usually accompany maturation, which is at odds with higher control stemming from formal organisations. This frustration, he contends, is detrimental to productivity, increases the chance of failure and causes conflict.

This book reports on new methodologies and important applications in the field of nanopolymers as well as includes the latest coverage of chemical databases and the development of new computational methods and efficient algorithms for chemical software and chemical engineering. The book provides an overview of the field, explains the basic underlying theory, and gives numerous comparisons of different methods. The new topics covered in this book will be an excellent resource for industries and academic researchers as well.

With chapters by the editors and other experts in the field of polymer science, this book covers a broad selection of important research advances in the field, including updates on enzymatic destruction and photoelectric characteristics, studies on the changes in the polymer molecular mass during hydrolysis and a new type of bioadditive for motor fuel, and an exploration of the interrelation of viscoelastic and electromagnetic properties of densely cross-linked polymers. Also included are chapters that discuss the problems of mechanics of textile performance, new aspects of polymeric nanofibers, a mathematical model of nanofragment cross-linked polymers, and much more.

A critical analysis of Argyris's Integrating The Individual and the Organization, which forms part of a series of essays and books considering how organisations should be run. The essay explores the lack of congruence between the needs and expectations of individual employees and the organisations that employ them. The impact of the work depends heavily on reasoning skills. Chris Argyris used strong, well-structured arguments to make his point. His reasoning has strong implications for solving a problem that many organizations experience: disengaged and disloyal employees. Grounding his argument in studies on human nature, Argyris highlighted that demands of greater independence, an expansion of interests, and re-orientation of goals usually accompany maturation, which is at odds with higher control stemming from formal organisations. This frustration, he contends, is detrimental to productivity, increases the chance of failure and causes conflict.

What makes a good manager? Though we can probably all point to someone we think of as a good manager, what precisely makes them so good at their job is a complex question - and one central to good business organization. Management scholar Douglas McGregor's seminal 1960 book The Human Side of Enterprise is perhaps the most influential attempt to answer that question, and provides an excellent example of strong evaluative and reasoning skills in action. Evaluation is all about judging the strength and weakness of positions: a critical evaluation asks how acceptable a line of reasoning is, how adequate, relevant and convincing the evidence is. McGregor sought to find out what makes a good manager by evaluating different management approaches, their assumptions about human behavior, and effects they had. In his view, management approaches could be roughly broken down into two "theories": Theory X, which held a negative idea of employee motivations; and Theory Y, which made positive assumptions about them. In McGregor's evaluation, Theory Y produced markedly better results in productivity and other measurable areas. On this basis, McGregor reasoned out a strong, persuasive argument for adopting Theory Y strategies on a grand scale.

US psychologist Abraham H. Maslow's A Theory of Human Motivation is a classic of psychological research that helped change the field for good. Like many field-changing thinkers, Maslow was not just a talented researcher, he was also a creative thinker - able to see things from a new perspective and show them in a different light. At a time when psychology was dominated by two major schools of thought, Maslow was able to forge a new, third paradigm, that remains influential today. Sigmund Freud's psychoanalysis had developed the idea of understanding the mind through dialogue between patient and analyst. The behaviorism of Ivan Pavlov and John Watson had focused on comprehending the mind through behaviors that could be measured, trained, and changed. Maslow, however, generated new ideas, forging what he called "positive" or "humanistic psychology". His argument was that humans are psychologically motivated by a series of hierarchical needs, starting with the most essential first. Maslow thought it important for the advancement of psychology to identify, group and rank these needs in terms of priority. His belief in the value of this third way was important in leading those who studied psychology to redefine the discipline, and so see it in new ways.

This book explains the complex relations and entanglements of Russia and its neighboring countries, an area that changed dramatically after the collapse of communism and the end of the Cold War. The chapters discuss how the strategic cultures of different countries display common characteristics rooted in this special geopolitical space that has been subjected to simultaneous changes over a longer time. Shared historical experiences provide a common ground to interpret outside threats. The spatial context is relevant in this volume because the focus is on a geopolitical in-between-ness. The position in between two ideologically, politically or economically divergent entities affects the states' security considerations, maneuvering space and policy perspectives. By cross-examining competing Russian and Western influences Miklossy and Smith create a persuasive context of regional political choices.

This book constitutes the refereed joint proceedings of the First International Workshop on Computational Pathology, COMPAY 2018, and the 5th International Workshop on Ophthalmic Medical Image Analysis, OMIA 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 19 full papers (out of 25 submissions) presented at COMPAY 2018 and the 21 full papers (out of 31 submissions) presented at OMIA 2018 were carefully reviewed and selected. The COMPAY papers focus on artificial intelligence and deep learning. The OMIA papers cover various topics in the field of ophthalmic image analysis.

This book constitutes the refereed joint proceedings of the International Workshop on Point-of-Care Ultrasound, POCUS 2018, the International Workshop on Bio-Imaging and Visualization for Patient-Customized Simulations, BIVPCS 2017, the International Workshop on Correction of Brainshift with Intra-Operative Ultrasound, CuRIOUS 2018, and the International Workshop on Computational Precision Medicine, CPM 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018.The 10 full papers presented at POCUS 2018, the 4 full papers presented at BIVPCS 2018, the 8 full papers presented at CuRIOUS 2018, and the 2 full papers presented at CPM 2018 were carefully reviewed and selected. The papers feature research from complementary fields such as ultrasound image systems applications as well as signal and image processing, mechanics, computational vision, mathematics, physics, informatics, computer graphics, bio-medical-practice, psychology and industry. They discuss intra-operative ultrasound-guided brain tumor resection as well as pancreatic cancer survival prediction.

This book constitutes the refereed joint proceedings of the 7th Joint International Workshop on Computing and Visualization for Intravascular Imaging and Computer Assisted Stenting, CVII-STENT 2018, and the Third International Workshop on Large-Scale Annotation of Biomedical Data and Expert Label Synthesis, LABELS 2018, held in conjunction with the 21th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 9 full papers presented at CVII-STENT 2017 and the 12 full papers presented at LABELS 2017 were carefully reviewed and selected. The CVII-STENT papers feature the state of the art in imaging, treatment, and computer-assisted intervention in the field of endovascular interventions. The LABELS papers present a variety of approaches for dealing with few labels, from transfer learning to crowdsourcing.

This book constitutes the refereed joint proceedings of the 4th International Workshop on Deep Learning in Medical Image Analysis, DLMIA 2018, and the 8th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 39 full papers presented at DLMIA 2018 and the 4 full papers presented at ML-CDS 2018 were carefully reviewed and selected from 85 submissions to DLMIA and 6 submissions to ML-CDS. The DLMIA papers focus on the design and use of deep learning methods in medical imaging. The ML-CDS papers discuss new techniques of multimodal mining/retrieval and their use in clinical decision support.

This book constitutes the refereed joint proceedings of the First International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2018, the First International Workshop on Deep Learning Fails, DLF 2018, and the First International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 4 full MLCN papers, the 6 full DLF papers, and the 6 full iMIMIC papers included in this volume were carefully reviewed and selected. The MLCN contributions develop state-of-the-art machine learning methods such as spatio-temporal Gaussian process analysis, stochastic variational inference, and deep learning for applications in Alzheimer's disease diagnosis and multi-site neuroimaging data analysis; the DLF papers evaluate the strengths and weaknesses of DL and identify the main challenges in the current state of the art and future directions; the iMIMIC papers cover a large range of topics in the field of interpretability of machine learning in the context of medical image analysis.