The first sweeping, legacy-defining history of the entire Obama presidency. Finalist of the PROSE Award for Best Book in Biography & Autobiography by the Association of American Publishers In The Black President, the first interpretative, grand-narrative history of Barack Obama's presidency in its entirety, Claude A. Clegg III situates the former president in his dynamic, inspirational, yet contentious political context. He captures the America that made Obama's White House years possible, while insightfully rendering the America that resolutely resisted the idea of a Black chief executive, thus making conceivable the ascent of the most unlikely of his successors. In elucidating the Obama moment in American politics and culture, this book is also, at its core, a sweeping exploration of the Obama presidency's historical environment, impact, and meaning for African Americans-the tens of millions of people from every walk of life who collectively were his staunchest group of supporters and who most starkly experienced both the euphoric triumphs and dispiriting shortcomings of his years in office. In Obama's own words, his White House years were "the best of times and worst of times" for Black America. Clegg is vitally concerned with the veracity of this claim, along with how Obama engaged the aspirations, struggles, and disappointments of his most loyal constituency and how representative segments of Black America engaged, experienced, and interpreted his historic presidency. Clegg draws on an expansive archive of materials, including government records and reports, interviews, speeches, memoirs, and insider accounts, in order to examine Obama's complicated upbringing and early political ambitions, his delicate navigation of matters of race, the nature and impacts of his administration's policies and politics, the inspired but also carefully choreographed symbolism of his presidency (and Michelle Obama's role), and the spectrum of allies and enemies that he made along the way. The successes and the aspirations of the Obama era, Clegg argues, are explicitly connected to our current racist, toxic political discourse. Combining lively prose with a balanced, nonpartisan portrait of Obama's successes and failures, The Black President will be required reading not only for historians, politics junkies, and Obama fans but also for anyone seeking to understand America's contemporary struggles with inequality, prejudice, and fear.

Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.

Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France. It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development. Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries. This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.

It is by no means a revelation that proteins are not uniformly distributed throughout the cell. As a result, the idea that protein molecules, because of the specificity with which they can engage in interactions with other proteins, may be aimed-via these interactions-at a restricted target, is a fundamental one in contemporary molecular life sciences. The target may be variously c- ceived as a specific molecule, a group of molecules, a structure, or a more generic type of intracellular environment. Because the concept of protein targeting is intuitive rather than expl- itly defined, it has been variously used by different groups of researchers in cell biology, biochemistry, and molecular biology. For those working in the field of intracellular signaling, an influential introduction to the topic was the seminal article by Hubbard & Cohen (TIBS [1993] 18, 172-177), which was based on the work of Cohen's laboratory on protein phosphatases. Sub- quently, the ideas that they discussed have been further developed and extended by many workers to other key intermediaries in intracellular sign- ing, including protein kinases and a great variety of modulator and adaptor proteins.

Water is 'n baie vreemde stof met ongewone eienskappe. Alhoewel daar baie water in die wereld is, is dit op sommige plekke baie skaars. In die noorde en suide van Afrika is daar wel baie water in die see, maar nie genoeg vars water op plekke waar mense dit nodig het nie. In Sentraal-Afrika, naby die ewenaar, is daar heelwat meer vars water. Plante en gewasse groei goed.

Daar is selfs gebiede wat met reenwoude bedek is. Hierdie boek sal jou van 'n hele paar nuwe feite bewus maak! Heinemann se Lees is Maklik-reeks bevat ‘n verskeidenheid stories vir die Intermediere Fase-leerder. Die leesboeke is ontwikkel deur taalspesialiste en onderwysers om die vaardighede in Afrikaans te bevorder en te verryk.

Die reeks dek ‘n verskeidenheid van genres: drama, komedie, avontuur, rillers, aksie, tradisionele stories, misterie en nie-fiksie. Elke graad bestaan uit 20 titels, ‘n totaal van 60 titels vir die Intermediere Fase met stimulerende leesstof vir lesse. Elke verhaal het opwindende illustrasies en aktiwiteite wat gebaseer is op die storie.

Kgang eno e ka ga metsi. O tla ithuta go le gontsi ka ga seedi seno. Ke eng le gore se re thusa ka eng mo botshelong. Gape kgang eno e tswelela go re lemosa gore metsi a tswa kwa kae. Metsi gape a kgona go nna dikgapetla le go nna phufudi. Buisa o ithute. Puiso ya Heinemann ya Go Buisa Go Bonolo ke motseletsele wa dipadisi tsa Puo ya gae o o nang le terama, metlae, metlholo, dimakatso le dikgangtota tsa moithuti wa Kgato ya Magareng.

Motseletsele ono o na le ditlhogo di le 20 go Mophato mongwe le mongwe mme di rulagantswe go tswa go 1 go ya go 4. Motseletsele ono o neela barutabana le baithuti mmogo mofuta wa didiriswa tsa go buisa go rotloetsa dithuto tsa phaposiborutelo.

Meetse ke selo sa go makatsa ka ge a dira dilo tse ntsi ts go se tlwaelege lefaseng. O ka hwetsa ka thoko tse dingwe ele a mantsi mola ka thoko tse dingwe a sego. Ga go sephedi se ka phelago ntle le meetse ka gore o ka phela matsatsi a mmalwa o sa je fela o kase phele ge o sanwe meetse ka fao meetse ke bophelo. Padi e tla go hlalosetsa mehuta ya meetse, mo pula e tswago le ka mo a tsosolosago tlhago. Moithuti o tla laetswa ka mo lefase le khupeditswego ke meetse. O tla hlalosetswa ka mehola ya meetse le mmeleng wa gago. Hlatlamano ya Go bala go bonolo ya Heinemann ya leleme la gae e na le tiragatso, tlhohlomiso, tsa go fega, semaka, boikgopolelo le dikanegelo tsa nnete tsa moithuti wa Sehlopha sa gare. Hlatlamano e na le palomoka ya dihlogo tse 20 ka kreiti gomme dihlogo tse di arogantswe magareng 1 go fitlhelela go 4. Dihlatlamano tsa Go bala go bonolo di abela morutisi yo mongwe le yo mongwe le baithuti ditlabelo tsa go bala tsa mehutahuta go tsosolosa dithutwana tsa kreiti.

Libali elingokubaluleka kwamanzi ebomini bethu. Kuchazwa nangeendlela ngeendlela amanzi aguquguquka ngayo abe yenye imo, umzekelo, abe ngumkhenkce nomphunga. Kuchatshazelwa nemvelaphi yemvula nemisebenzi yamanzi jikelele. Imvelaphi yamanzi, iilwandle nokukhuseleka kwawo ukuba aselwe yeminye imiba echatshazelwayo kweli bali.

Ungcoliseko lwamanzi ngomnye umbandela ophambili ochatshazelwayo kakhulu kwibali eli. Iincwadi zakwaHeinemann zokufunda ezithi Ukufunda Kulula, zoLwimi lwasekhaya ziqulethe iidrama, iziyolisi, amabali angobukroti nobuqhawe, amabali adala unxunguphalo, amabali angolunqa, amabali abuntsomirha kunye nalawo ayinyani alungiselelwe umfundi wesiGaba esiPhakathi.

Olu luhlu lunamabali angama-20 kwibanga ngalinye, elo nelo bali linikwe umgangatho phakathi kowokuqala ukuya kowesine. Uluhlu lokufunda luka-Ukufunda Kulula lwenza abafundi bakuvuyele ukufunda kwaye bakwazi nokuphucula ukufunda kwabo eklasini.