This text is appropriate for those courses with an emphasis on e-commerce and the Internet, as well as short courses or MBA/IS courses that want a modern approach. Networking has changed dramatically over the past ten years. Most texts have focused on network layers and their concepts and then on how the different technologies are implemented; however with the number of viable technologies shrinking, it makes less sense to focus on concepts first and technologies second. Networking in the Internet Age first edition integrates the discussion of concepts and technologies so they appear in one place, organized by layers.

Required reading for anyone involved in cell signaling research with articles written and edited by experts in the field. This title covers disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, andinflammatory bowel disease, along with up-to-date research on signaling systems and mutations in
transcription factors that provide new targets for treating disease.
Articles written and edited by experts in the field
Thematic volume covering disease states such as lymphoid leukemia, breast cancer, pulmonary fibrosis, systemic sclerosis, and inflammatory bowel disease
Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.

Articles written and edited by experts in the field
Thematic volume covering material needed for young professionals joining the field of research and graduate students taking survey courses
Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

This must-have cell signaling title will appeal to researchers across molecular biology, biochemistry, cell biology and genetics. The articles are written and edited by experts in the field and emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, the regulation of endoplasmic reticulum function, control of cell cycle progression and apoptosis and the modulation of the activities of mitochondria and other organelles.

Articles written and edited by experts in the field
Thematic volume covering regulation of endoplasmic reticulum function, regulation of cell cycle progression, and quality control and assurance in mitochondrion events
Up-to-date research on events in membrane proteins and proteins of intracellular matrix

A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation.

Articles written and edited by experts in the field
Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events
Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease

This collection re-evaluates the work of fifteenth-century poet John Lydgate in light of medieval material culture. Top scholars in the field unite here with critical newcomers to offer fresh perspectives on the function of poetry on the cusp of the modern age, and in particular on the way that poetry speaks to the heightened relevance of material goods and possessions to the formation of late medieval identity and literary taste. Advancing in provocative ways the emerging fields of fifteenth-century literary and cultural study, the volume as a whole explores the role of the aesthetic not only in late medieval society but also in our own.

This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.

A thorough review of general mathematics and its applications in radiography as well as a handy reference for basic formulas and calculations used by radiographers. This book starts with basic mathematic principles and moves on to present the reader with the calculations required to produce high quality radiographic images and practice problems which aid in the understanding of these calculations. Areas discussed include mAs conversions, inverse square law, radiographic density and contrast, screens and grid ratios, grid conversions, geometric and magnification unsharpness, and graphs and conversions between conventional and systems international (SI) units of radiation dosimetry. No other book provides such clear instruction for radiographic calculations. A handy Instructor's Manual is also available.

Selenium is a naturally occurring trace element that can become concentrated and released by industrial, agricultural, petrochemical and mining activities. At concentrated levels it is toxic and has polluted ecosystems around the world. This book will serve as a comprehensive practical handbook for everyone dealing with selenium in aquatic environments. It offers field-tested approaches and methods for assessment and water quality management. Using his twenty-year experience, the author discusses the effects of selenium on fish and bird populations and presents guidelines for identifying sources of pollution, interpreting selenium concentrations, assessing hazardous conditions, setting water quality criteria and ecosystem loading limits (TMDLs). He also includes a procedure for setting environmentally safe limits that ensure compliance with EPA regulations. Selenium Assessment in Aquatic Ecosystems will interest field scientists, natural resource managers, risk assessors and environmental planners.

KEY FEATURES:
* Contains over 350 chapters of comprehensive coverage on cell signaling
* Includes discussion on topics from ligand/receptor interactions to organ/organism responses
* Provides user-friendly, well-illustrated, reputable content by experts in the field
DESCRIPTION:
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors.

Social interaction lies at the heart of our everyday experience. We make our way down the street and avoid crashing into others, take our place in the supermarket queue, take care in the way we talk about others in conversation, acknowledge the social status of people we meet, and enjoy leisurely pursuits in the company of friends and like-minded others. All these things are fundamental parts of human sociality that can be discovered and understood through sociologies of interaction'. This book provides an invaluable introduction to the theoretical foundations and practical applications of interactionist approaches to everyday life. Beginning with an overview of three core traditions - symbolic interactionism, ethnomethodology and conversation analysis, along with Goffman's work on the interaction order - the text moves on to examine in detail topics such as leisure, work, health and illness, deviance, class, status and power, education, ethnic relations and gender. Highlighting a range of empirical studies, the book shows how sociologies of interaction have the capacity to reframe and make us rethink conventional social science topics. This illuminating book will be of interest to undergraduates across the social sciences, particularly in sociology, social psychology and communication studies, as well as those who have an interest in understanding the interactional underpinnings of everyday life.

Since their discovery over 60 years ago, eicosanoids have come to represent a diverse family of bioactive lipid modulators, including prostaglandins, thromboxanes, leukotrienes, lipoxins, isoprostanes, hepoxilins, hydroxy acids, epoxy and hydroxy fatty acids. This book contains conference presentations regarding the regulation of eicosanoid enzymes and, in particular, cyclooxygenases, lipoxygenases, and phospholipases. In addition, the latest evidence over the last seven years has led to the identification of a number of receptors for these bioactive lipids. The new field of isoprostanes is also represented. It has become increasingly evident that eicosanoids play a critical role in signal transduction, both in normal cells and in pathological processes. These aspects are discussed in relation to cellular events, such as apoptosis, angiogenesis, and cancer prevention and treatment.

This volume represents a collection of contributions from the 6th International Conference on Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation, and Related Diseases held in Boston from September 12-15, 1999. The mission of this meeting was to bring together senior and junior investigators to both announce and examine their recent advancements in cutting-edge research on the roles and actions of lipid mediators and their impact in human physiology and disease pathogenesis. The meeting focused on new concepts in these areas of interest to both clinicians and researchers. The program included several outstanding plenary lectures and presentations by leading experts in the fields of cancer and inflammation. In addition, the Boston meeting presented three Young Investigator awards, one in each of the major focus areas. The meeting was exciting and proved to be very memorable. The program was developed with an emphasis on recent advances in molecular and of lipid mediators relevant in cellular mechanisims involved in the formation and actions inflammation and cancer. Plenary lectures were presented by Prof. Bengt Sammuelsson (Karolinska Institute, Stockholm; 1982 Nobel Laureate in Physiology or Medicine) and Prof. E. 1. Corey (Harvard University; 1990 Nobel Laureate in Chemistry). Both of these plenary lectures were held on Day 1, which set an exciting tone for this meeting. Immediately following these plenary lectures, three simultaneous breakout sessions were held, one of inflammation, a second on cancer and synthesis of novel inhibitors, and a third on enzymes-lipoxygenases/cyclooxygenases and inhibitors.

Selenium is a naturally occurring trace element that can become concentrated and released by industrial, agricultural, petrochemical and mining activities. At concentrated levels it is toxic and has polluted ecosystems around the world. This book will serve as a comprehensive practical handbook for everyone dealing with selenium in aquatic environments. It offers field-tested approaches and methods for assessment and water quality management. Using his twenty-year experience, the author discusses the effects of selenium on fish and bird populations and presents guidelines for identifying sources of pollution, interpreting selenium concentrations, assessing hazardous conditions, setting water quality criteria and ecosystem loading limits (TMDLs). He also includes a procedure for setting environmentally safe limits that ensure compliance with EPA regulations. Selenium Assessment in Aquatic Ecosystems will interest field scientists, natural resource managers, risk assessors and environmental planners.

This volume in the Advances in Experimental Medicine and Biology Series is dedicated to developing an overall view of the "state-of the-art" of knowledge in the field of phospholipase A2 and to exploring the role and function of this enzyme in various inflammatory diseases. This book grew out of two major symposia on phospholipase A2 held in 1989: I). "Phospholipase A2: Pathophysiological Role of Soluble and Membrane-Bound Enzymes" organized by Dr. Doug Morgan and Dr. Ann Welton of Hoffmann-La Roche and sponsored by the New York Academy of Sciences (January 24, 1989). II). "Release and Function of Phospholipase A2 from Inflammatory Cells" organized by Dr. Patrick Wong and Dr. Edward Dennis at the FASEB meeting in New Orleans (March 22, 1989). Readers will find exciting advances in our understanding of the structure, function and molecular biology of phospholipase A2 research which is presented in this volume. The elucidation of gene structures of phospholipase A2 should lead to new insights and new approches in the control and regulation of the enzyme activity. This is primary to better understanding the function of phospholipase A2 and the determination of its activity in cellular and animal systems. Of great importance is the development of animal models for inflammatory disease in order to evaluate the role of phospholipase A2 and its inhibitors. We are convinced that this volume will be an excellent reference that surveys this field in which numerous investigators are currently actively at work.

This multi-contributed, comprehensive book covers revision surgery for total hip and knee arthroplasty. The focus of Revision Total Hip and Knee Arthroplasty will be on the techniques of revision surgery. Separated into a hip section and a knee section, each will include evaluation of the failed replacement, revision surgery, surgical technique, revision for specific diagnosis, complications, and postoperative management.

How can we provide guarantees of behaviours for autonomous systems such as driverless cars? This tutorial text, for professionals, researchers and graduate students, explains how autonomous systems, from intelligent robots to driverless cars, can be programmed in ways that make them amenable to formal verification. The authors review specific definitions, applications and the unique future potential of autonomous systems, along with their impact on safer decisions and ethical behaviour. Topics discussed include the use of rational cognitive agent programming from the Beliefs-Desires-Intentions paradigm to control autonomous systems and the role model-checking in verifying the properties of this decision-making component. Several case studies concerning both the verification of autonomous systems and extensions to the framework beyond the model-checking of agent decision-makers are included, along with complete tutorials for the use of the freely-available verifiable cognitive agent toolkit Gwendolen, written in Java.

This book constitutes the thoroughly refereed post-conference proceedings of the 7th International Workshop on Engineering Multi-Agent Systems, EMAS 2019, held in Montreal, QC, Canada, in May 2019. The 13 revised full papers presented in this book were carefully selected and reviewed from 20 submissions. The papers are grouped in the following topical sections: Multi-Agent Interaction and Organization; Simulation; Social Awareness and Explainability; Learning and Reconfiguration; and Implementation Techniques and Tools.

This collection re-evaluates the work of fifteenth-century poet John Lydgate in light of medieval material culture. Top scholars in the field unite here with critical newcomers to offer fresh perspectives on the function of poetry on the cusp of the modern age, and in particular on the way that poetry speaks to the heightened relevance of material goods and possessions to the formation of late medieval identity and literary taste. Advancing in provocative ways the emerging fields of fifteenth-century literary and cultural study, the volume as a whole explores the role of the aesthetic not only in late medieval society but also in our own.

A critical issue in dealing with climate change is deciding who has a right to emit carbon dioxide. Originally published in 2007, Allocation in the European Emissions Trading Scheme provided the first in-depth description and analysis of the process by which rights to emit carbon dioxide were created and distributed in the European Union. This was the world's first large-scale experiment with an emission trading system for carbon dioxide and was likely to be copied by others if there was to be a global regime for limiting greenhouse gas emissions. The book comprises contributions from those responsible for putting the allocation into practice in ten representative member states and at the European Commission. The problems encountered in this process, the solutions found, and the choices they made, will be of interest to all who are concerned with climate policy and the use of emissions trading to combat climate change.

The European Union's Emissions Trading Scheme (EU ETS) is the world's largest market for carbon and the most significant multinational initiative ever taken to mobilize markets to protect the environment. It will be an important influence on the development and implementation of trading schemes in the US, Japan, and elsewhere. However, as is true of any pioneering public policy experiment, this scheme has generated much controversy. Pricing Carbon provides the first detailed description and analysis of the EU ETS, focusing on the first 'trial' period of the scheme (2005-7). Written by an international team of experts, it allows readers to get behind the headlines and come to a better understanding of what was done and what happened based on a dispassionate, empirically based review of the evidence. This book should be read by anyone who wants to know what happens when emissions are capped, traded, and priced.

A critical issue in dealing with climate change is deciding who has a right to emit carbon dioxide. Allocation in the European Emissions Trading Scheme provided the first in-depth description and analysis of the process by which rights to emit carbon dioxide were created and distributed in the European Union. This was the world's first large-scale experiment with an emission trading system for carbon dioxide and was likely to be copied by others if there was to be a global regime for limiting greenhouse gas emissions. The book comprises contributions from those responsible for putting the allocation into practice in ten representative member states and at the European Commission. The problems encountered in this process, the solutions found, and the choices they made, will be of interest to all who are concerned with climate policy and the use of emissions trading to combat climate change.

A comprehensive description and evaluation of the first three years of the U.S. Acid Rain Program. This environmental control program is the world's first large-scale use of a tradeable emission permit system for achieving environmental goals. The book analyzes the behavior and performance of the market for emissions permits, known as allowances, and quantifies emission reductions, compliance costs, and cost savings associated with the trading program. The book also includes chapters on the historical context in which this pioneering program developed and the political economy of allowance allocations. Finally, the book discusses the program's successes, its weaknesses, and the lesson learned regarding application of the emissions-trading approach to controlling other types of emissions, including greenhouse gases. The volume is an indispensable addition to the library of all interested in the application of marker principles for meeting environmental goals.

Markets for Clean Air provides a comprehensive, in-depth description and evaluation of the first three years' experience with the U.S. Acid Rain Program. This environmental control program is the world's first large-scale use of a tradable emission permit system for achieving environmental goals. The book analyzes the behavior and performance of the market for emissions permits, called allowances in the Acid Rain Program, and quantifies emission reductions, compliance costs, and cost savings associated with the trading program. The book also includes chapters on the historical context in which this pioneering program developed and the political economy of allowance allocations.