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The 40th volume of "Methods in Microbiology" focuses on microbial synthetic biology. Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems. This volume addresses some of the major technical challenges
stand in the way of achieving a radical step-change in our ability
to engineer complex multi-scaled biological systems. These include:
the application of computation intelligence to the design of
synthetic microbial systems, design automation and constraints; the
impact of noise and stochasticity; the engineering of biosensors;
the characteristic of a model bacterial chassis. A key issue in
Synthetic Biology is that of its social dimensions and a chapter is
dedicated to the important issue.
Focusing on the systems biology of bacteria and microorganisms, the
39th volume of "Methods in Microbiology"investigates the interface
between molecular biology, bioinformatics, and modelling" "and
predicting behavior. This cutting-edge research area is of extreme
importance to the field and is developing quickly.
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