G Protein-Coupled Receptors: Emerging Paradigms in Activation, Signaling and Regulation, Part A, Volume 337 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This new release includes comprehensive sections on the classical paradigms of GCPR signaling and regulation, the family of small GTPases: Beyond heterotrimeric G proteins, GPCR endocytosis: Arrestins, arrestin-like proteins, signaling from internalized G Protein-Coupled Receptors, GPCR kinases, and more.

Student feedback has appeared in the forefront of higher education quality, particularly the issues of effectiveness and the use of student feedback to affect improvement in higher education teaching and learning, and other areas of the students tertiary experience. Despite this, there has been a relative lack of academic literature available, especially in a book format. This book focuses on the experiences of academics, higher education leaders and managers with expertise in these areas.
Enhancing Learning and Teaching through Student Feedback in Engineering is the first in a series on student feedback focusing on a specific discipline, in this case engineering. It expands on topics covered in the previous book, by the same authors. Valuable contributions have been made from a variety of experts in the area of higher education quality and student feedback in the field of engineering.
Will interrogate student feedback in engineering, on the basis of establishing a better understanding of its forms, purposes and effectiveness in learningThe first book of its kind on student feedback in engineering education and will be a scholarly resource for all stakeholders to enhance learning and teaching practices thorough student feedbackWritten by experienced academics, experts and practitioners in the area"

The aim of this report is to analyse and assess the policy landscape faced by UK energy users both households and firms and explore the potential forimprovement. We highlight a number of reform options and recommendationsfor firm and household energy use policies. They include some changes that could be implemented quickly and more radical reforms that would require further consultation and time.http: //www.cccep.ac.uk/Publications/Policy/docs/energy-policies-carbon-pricing-uk.pd

Comparing the structures and challenges of democratic constitutionalism in India and the European Union, this book explores how democracy is possible within vastly diverse societies of continental scale, and why a constitutional framework is best able to secure the ideals of collective autonomy and individual dignity. It contributes to an emerging comparative discussion on structures of power, separation of powers and a comparative law of democracy, which has been long neglected in comparative constitutional studies. This timely and invigorating book showcases a novel comparative approach termed "slow comparison" counters the conceptual focus on nation-states in comparative studies and develops a broader understanding of democratic constitutionalism. In the context of the contemporary crisis of constitutional democracy, triggered by populism, majoritarianism and authoritarianism, chapters continue older ongoing debates about multiculturalism, identity politics and democratic equality that hold important insights for both India and the EU to deal with contemporary challenges. This book will be an important read for scholars of comparative constitutional law and theory. It will also benefit those studying EU law and Indian constitutional law.

Providing a much-needed study on cybersecurity regime building, this comprehensive book is a detailed analysis of cybersecurity norm-making processes and country positions, through the lens of multi-stakeholder diplomacy. Multi-disciplinary and multi-national scholars and practitioners use insights drawn from high-level discussion groups to provide a rigorous analysis of how major cyber powers view multi-stakeholder diplomacy. Looking at how past cybersecurity initiatives and multi-stakeholder negotiations in other fields illuminate its dynamics, this book will help put states' approaches towards multi-stakeholder cyber diplomacy into perspective, and frame the role of private actors in cybersecurity regime building. Evaluating the most promising institutional arrangements and mechanisms for implementing cybersecurity, this book combines top-down analyses relevant to the design of international cybersecurity regimes with bottom-up case studies, tracing the approaches of important states towards multi-stakeholder participation in cyber diplomacy. With a wealth of policy-relevant findings, this book will be welcomed by practitioners and scholars of international law, international organisation and international cybersecurity as well as multi-stakeholder governance and multilateral regimes. Policymakers and diplomats involved in international cybersecurity processes will also benefit from its cutting-edge comparative analysis of the approaches of key cyber powers.

Biocomposites – Bio-based Fibres and Polymers from Renewable Resources: Processing, Performance, Durability and Applications provides a systematic and comprehensive review of recent developments in this important area of research. Chapters discuss novel techniques for processing and the characterization of biocomposites derived from renewable resources, focusing on durability, strength prediction, aging methods and performance evaluation. Future trends, directions and opportunities are also addressed. Readers will find an up-to-date summary of recent research findings that have been conducted on biocomposites, making this an essential reference resource for academic and industrial researchers and anyone working in the development of innovative materials from renewable resources.

Role of Green Chemistry in Ecosystem Restoration to Achieve Environmental Sustainability deals with current challenges of environmental problems along with the approaches of environmental sustainability in alliance with green chemistry. The book shows how to lessen the impact on the environment by maintaining a balance between society, the environment, and the economy, all of which are regarded as fundamental pillars of sustainability. Furthermore, policymakers and scholars will gain insights into how to develop and explore innovative techniques for achieving sustainable development goals. This book is unique in the field of environmental sustainability, as it is based on green chemistry concepts.

Water Resources Management for Rural Development: Challenges and Mitigation provides an overview of the current challenges of rural water and its management strategies. The content contains practical and theoretical aspects of the water crisis in rural areas in a changing climate era, with an emphasis on recent water crisis research and management strategies. The book's structure contains fundamentals of water resources, pollution, remediation, supply and management strategies. Case studies included provide different water-related issues around the globe, introducing the reader to the paths of reducing the burden on the groundwater and the alternative options for the supply of water in rural areas. Decision-makers and water supply authorities will benefit from this unique resource that comprehensively covers rural water management in ways no comparable book has achieved.

Integrated Methods in Protein Biochemistry: Part C, Volume 679 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including NanoBiT-based methods to monitor the activation and modulation of RTKs, The interplay of G-protein ss? subunit and PLC-ss enzyme in PIP2 hydrolysis and downstream signaling, Biochemical Analysis of Protein-Protein Interfaces underlying the regulation of Bacterial Secretion Systems, Probing the structure and function of N-acetylmannosamine-6-phosphate 2-epimerase, Spectroscopic analysis of cysteine dioxygenase: a mammalian thiol-dioxygenase, DeGlyPHER: MS-based analysis of viral spike N-glycoforms, and more. Other sections cover Covalent protein painting: MS-based protein footprinting, Characterization of GPCR signaling complexes using negative-staining electron microscopy, Probing protein misfolding and dissociation with free electron laser, Optimized protocol for the characterization of Cas12a activities, Proximity proteomics for the identification and characterization of extracellular vesicles, Functional characterization of lytic polysaccharide monooxygenases (LPMOs), Characterization of RRE domain in RiPP biosynthesis, The Preparation of Recombinant Arginyltransferase 1 (ATE1) for Structural and Biophyiscal Characterizations, Testing anti-cancer drugs with Holographic Incoherent-light-source Quantitative Phase Imaging, and more.

G Protein-Coupled Receptors, Part B, Volume 195 represents the largest class of cell H103 surface proteins that have intricate involvement in nearly every physiological process in our body. Approximately one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. Sections in this volume include Adhesion G protein-coupled receptors: Structure and functions, Molecular and cellular mechanisms underlying brain region-specific cannabinoid receptor modulation by estradiol across the rodent estrus cycle, Probing the orphan receptors: Tools and directions, Asymmetric activation of Class C GPCRs, Common and selective signal transduction mechanisms of GPCRs, and much more.

Integrated Methods in Protein Biochemistry: Part B, Volume 678 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Precise modification of native proteins, purification, and analysis of bioconjugates, NanoBiT-based methods to monitor the activation and modulation of RTKs, The interplay of G-protein ss? subunit and PLC-ss enzyme in PIP2 hydrolysis and downstream signaling, Structure and function of bacterial secretion system, Tools and protocols for probing protein sumoylation, Spectroscopic analysis of cysteine dioxygenase: a mammalian thiol-dioxygenase, DeGlyPHER: MS-based analysis of viral spike N-glycoforms, and more. Additional sections cover Covalent protein painting: MS-based protein footprinting, Characterization of GPCR signaling complexes using negative-staining electron microscopy, Probing protein misfolding and dissociation with free electron laser, Optimized protocol for the characterization of Cas12a activities, Proximity proteomics for the identification and characterization of extracellular vesicles, Structural and Functional characterization of lytic polysaccharide monooxygenases, and much more.

Nanotechnology Applications for Food Safety and Quality Monitoring brings together nanotechnology science-based research for food safety and quality monitoring. With the advancement in knowledge about behavior of nano-engineered materials in food and its toxicity, the application of nanotechnology is expected to reach unprecedented levels in achieving food safety. Currently, there is no practical resource of nanotechnology as a tool specifically for monitoring safety and quality. This is a practical, concise, applications-based reference that is essential for food industry researchers and scientists to monitor the safety and quality of food to ensure quality food supplies.

Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents. This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology.

Cellulose Fibre Reinforced Composites: Interface Engineering, Processing and Performance provides an up-to-date review of current research in cellulose fiber reinforced polymer composites. Key emphasis is placed on interface engineering, modern technologies needed for processing and materials performance in industrial applications. Novel techniques for interfacial adhesion, characterization and assessment of cellulose fiber reinforced composites are also discussed, along with current trends and future directions. With contributions from leading researchers in industry, academic, government and private research institutions from across the globe, the book will be an essential reference resource for all those working in the field of cellulose fibers and their composites.

G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.

Integrated Methods in Protein Biochemistry: Part A, Volume 677, the latest release in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as DNA and protein engineering to create protein bioswitches with new functions, Interaction and cross-talk of prelamin A with integral membrane zinc metalloproteases, An experimental protocol to study lipid transfer proteins, Synthesis of small heat shock proteins, Druggable p-p interacting sites for Co-chaperone DNAJA1 and its partner proteins, An experimental protocol for glycoconjugate analysis, Methods for proximity-based biotinylation combined with Mass Spectrometry, and more. Additional chapters cover Synthetic antibody fragments as conformational sensors of protein activation and trafficking, Expression, purification, functional analysis and crystallization of Rag GTPase, Purification of bacterial transcription elongation complexes by photoreversible immobilization, Inhibition of c-Myc-MAX heterodimerization, Fluorogenic RNA aptamers to probe transcription by multi-subunit RNA polymerases, and much more.

Artificial Intelligence for Renewable Energy Systems addresses the energy industries remarkable move from traditional power generation to a cost-effective renewable energy system, and most importantly, the paradigm shift from a market-based cost of the commodity to market-based technological advancements. Featuring recent developments and state-of-the-art applications of artificial intelligence in renewable energy systems design, the book emphasizes how AI supports effective prediction for energy generation, electric grid related line loss prediction, load forecasting, and for predicting equipment failure prevention. Looking at approaches in system modeling and performance prediction of renewable energy systems, this volume covers power generation systems, building service systems and combustion processes, exploring advances in machine learning, artificial neural networks, fuzzy logic, genetic algorithms and hybrid mechanisms.

Biomolecular Interactions: Part A, Volume 169, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Emerging Mechanisms of Targeted Protein Degradation by Molecular Glues, Design and use of programmable DNA Hydrogels, Oligomerization of membrane receptors: Approaches to measure in live cells, Interactions of alpha-synuclein with biomolecules, Gel-electrophoresis based method for biomolecular interaction, Recombinant centrosome expression in bacterial system, Reconstituting CCL5-CCR5 complex for structural and mechanistic analysis, Protein engineering and design in ion channel receptors, and much more.

Climate Change and Crop Stress: Molecules to Ecosystems expounds on the transitional period where science has progressed to 'post-genomics' and the gene editing era, putting field performance of crops to the forefront and challenging the production of practical applicability vs. theoretical possibility. Researchers have concentrated efforts on the effects of environmental stress conditions such as drought, heat, salinity, cold, or pathogen infection which can have a devastating impact on plant growth and yield. Designed to deliver information to combat stress both in isolation and through simultaneous crop stresses, this edited compilation provides a comprehensive view on the challenges and impacts of simultaneous stresses.

Cognitive Systems and Signal Processing in Image Processing presents different frameworks and applications of cognitive signal processing methods in image processing. This book provides an overview of recent applications in image processing by cognitive signal processing methods in the context of Big Data and Cognitive AI. It presents the amalgamation of cognitive systems and signal processing in the context of image processing approaches in solving various real-word application domains. This book reports the latest progress in cognitive big data and sustainable computing. Various real-time case studies and implemented works are discussed for better understanding and more clarity to readers. The combined model of cognitive data intelligence with learning methods can be used to analyze emerging patterns, spot business opportunities, and take care of critical process-centric issues for computer vision in real-time.

Cognitive Big Data Intelligence with a Metaheuristic Approach presents an exact and compact organization of content relating to the latest metaheuristics methodologies based on new challenging big data application domains and cognitive computing. The combined model of cognitive big data intelligence with metaheuristics methods can be used to analyze emerging patterns, spot business opportunities, and take care of critical process-centric issues in real-time. Various real-time case studies and implemented works are discussed in this book for better understanding and additional clarity. This book presents an essential platform for the use of cognitive technology in the field of Data Science. It covers metaheuristic methodologies that can be successful in a wide variety of problem settings in big data frameworks.

Biomolecular Interactions: Part A, Volume 166, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics in cell biology. Each chapter is written by an international board of authors.