Bioconjugated Materials Part 2, Volume 103 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on bioconjugated materials. Each chapter is written by an international board of authors.

Clinical Trial Project Management provides a detailed overview of how to conduct clinical trials, in an international context. The process of conducting clinical studies across nations is based on a set of regulatory regimes developed by respective regulatory agencies. The book focuses on clinical study protocol approval processes, Ethics Committee approval processes, clinical study feasibilities, site selection, site initiation, site monitoring, database lock, sit close-out, clinical data processing and management, SAE reporting and compensation, randomization procedure, pharmacovigilance, statistical tools, BA/BE studies, and clinical study report writing etc. covering entire clinical trial process of conductance. In addition to that the author also incorporated the clinical trial approval process of USFDA, EMA, and JAPAN to conduct the clinical trials.

Advances in Nanotechnology for Marine Antifouling surveys the latest research in the application of nanotechnology for biofouling inhibition. The book gathers in-depth information on the various micro and nano-techniques, nanocoatings, polymeric composites paints, methods of application and prevention mechanisms. This is a valuable resource for researchers and advanced students across anti-biofouling, nanotechnology, nanomaterials, polymer nanocomposites, coatings, maritime technology, chemistry, chemical engineering, environmental science, and materials science and engineering. This is also essential reading for industrial scientists, engineers, R&D, and other professionals with an interest in the use of nanotechnology for antifouling, particularly in the maritime sector. Nanotechnologies have been recognized as a powerful tool in antifouling strategies with nanocoatings with efficient properties enabling increased durability and performance in the prevention of biofouling and corrosion while replacing potentially more harmful chemicals.

Nanomaterials for Bioreactors and Bioprocessing Applications explores the potential of nanomaterials in improving the efficiency of bioprocessing industries and next-generation bioreactors. The book provides information on various newly synthesized nanomaterials in bioreactors for scaling up the bioprocess to an industrial level, the criteria and properties of nanomaterials to be used in bioprocessing, advantages, challenges while using the nanomaterials, and the economic constraints. In addition, the book also discusses the fate of various nanomaterials in the bioprocess, the chances of product contamination and its prevention. This book is an important reference source for materials scientists and biomedical engineers information on the synthesized nanomaterials that are available for bioreactors and bioprocesses, and the various optimized conditions and precautions to be taken.

Nanotechnology for Advanced Biofuels: Fundamentals and Applications highlights emerging techniques for the formulation of fuels using nanotechnology and bio-based concepts. The addition of high-energy nanoparticles and biologically derived molecules in liquid fuel can increase the potential of energy-rich compounds. Key challenges in the production of nanotechnology-based fuels and their combustion or ignition during the operation are covered, along with the emission of oxidized particles and by-products of incomplete combustion and nano-fuels as an emerging field. The bio-based energy-rich fuels are largely diffused in conventionally used fuels. The addition of biofuels and nano-additives to pre-existing fuels can offer opportunities for developing modified fuels in domestic industries with the maximum usage of renewable biomass. This is an important reference source for materials scientists, energy scientists and chemical engineers who want to understand more about how nanotechnology can help create more efficient biofuels.

Smart Nanomaterials for Bioencapsulation focuses on the fundamentals, synthesis methods and matrix design for the encapsulation of drugs, drug release, food and nutraceuticals, mechanisms of nano- encapsulated drugs on liposomes, micelles, silica composites, carbon nanotubes, dendrimers, and protein inorganic nanohybrids. Providing detailed information on the encapsulation of food and drug derivatives, the book helps create new and modern approaches for both pharmaceutical and nutritional science. The target delivery of pharmacological agents, as well as food additives under various conditions is covered, including sections on systemic release of drug molecules, minimum loss at non-target sites, the accumulation of diseased tissue or organs, and more. Smart nanomaterial-based nanocarriers protect the loaded molecules from premature degradation in the biological environment and enhance bioavailability for cellular uptake. The tuned properties of smart nanomaterials, such as porosity, pore-volume, surface area-to-volume ratio, coating with inert and labile materials, and more help determine the in vivo performance of the bioencapsulated food and drug derivatives.

CO2-philic Polymers, Nanocomposites and Chemical Solvents: Capture, Conversion and Industrial Products is a multidisciplinary book that provides a compilation of concrete information on various polymers, porous materials hydrogels, membranes, nanoparticles, biochar metal-organic frameworks, bioinspired surfaces, polysaccharides, organic solvents, chemicals, eutectic solvents, amine-based chemical compounds, porphyrins, ionic liquids, ceramics and cutting-edge technologies for CO2 sequestration and conversion. Each chapter covers the latest developments and methods of synthesis and applications in the area. The book discusses, in detail, valuable commercial products from CO2, such as ethanol, methanol, formic acid, and precursors of other fine chemicals. The book covers the scientific, technological and practical concepts concerning the research, development and realization of CO2-philic polymers, nanocomposites and chemical solvents. This makes it a valuable resource for academic researchers and graduate students in chemical engineering, materials science and chemical engineers/engineers working in the industry.

Industrial wastewater contains a large variety of compounds, such as hazardous organic pollutants, heavy metals, salts and nutrients, which makes its treatment challenging. On the other hand, the sewage treatment with existing technologies is not cost-effective due to high energy demand and contributes to greenhouse gas emission. Thus, the use of conventional water treatment methods is neither sustainable nor always effective. In this sense, BESs has emerged as a promising technology to treat complex industrial wastewater with a sustainable manner. Development in Wastewater Treatment Research and Processes: Bioelectrochemical Systems for Wastewater Management analyses and discusses the potential of microbial and electrochemical based hybrid processes for the treatment of complex industrial wastewater along with the recovery of valuable compounds and water reutilization. The most significant advantages of BES are high effectiveness, low toxicity, gentle operation conditions, environmentally friendly treatment without sludge accumulation and energy conservation. Bioelectrochemical systems (BES) are emerging as an exciting platform to convert chemical energy of organic wastes into electricity or hydrogen or value-added chemical commodities. In addition, recent and future trends in BES are highlighted.

Nanomaterials for Electrocatalysis provides an overview of the different types of nanomaterials, design principles and synthesis protocols used for electrocatalytic reactions. The book is divided into four parts that thoroughly describe basic principles and fundamental of electrocatalysis, different types of nanomaterials used, and their electrocatalytic applications, limitations and future perspectives. As electrochemical systems containing nanomaterials, with relevance to experimental situation, yield better results, this book highlights new information and findings.

Nanotechnology in Paper and Wood Engineering: Fundamentals, Challenges and Applications describes recent advances made in the use of nanotechnology in the paper and pulp industry. Various types of nano-additives commonly used in the paper industry for modification of raw material to enhance final products are included, with other sections covering the imaging applications of nano-papers and nano-woods in pharmaceuticals, biocatalysis, photocatalysis and energy storage. This book is an important reference source for materials scientists and engineers who are looking to understand how nanotechnology is being used to create more efficient manufacturing processes in for the paper and wood industries.

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.

Nanosensors for Smart Agriculture covers new breakthroughs in smart agriculture, highlighting new technologies, such as the internet of things, big data and artificial intelligence. In addition, the book provides the many advantages of nanosensors over their micro counterparts, such as lower power consumption, higher sensitivity, lower concentration of analytes, and smaller interaction distances between the object and sensor. Sections provide information on fundamental design concepts and emerging applications of nanosensors in smart agriculture. The book highlights how, when cultivating soil, nanosensors and their wireless networks can be used for soil quality monitoring (moisture/herbicides/organic compound/trace metals monitoring in soil, etc. Other applications cover how smart nanosensors can be used for virus detection and hygiene/pathogen controls in livestocks, their use as active transport tracking devices for smart tracking and tracing, and other various applications, such as (i) nanochips for identity (radio frequency identification), (ii) food inspection, (iii) intelligent food packaging, and (iv) smart storage. This is an important reference source for materials scientists and agricultural engineers who are looking to understand more about how nanosensor technology can be used to create more efficient and sustainable agricultural systems.

Diagnostic, Prognostic and Therapeutic Role of MicroRNAs in Head and Neck Cancer provides detailed information on various miRNA-based approaches for the diagnosis, prognosis, and treatment of HNSCC. The book encompasses various miRNA-based point-of-care diagnostics and drug delivery systems for HNSCC, along with information on clinical trials for improved clinical outcomes in HNSCC patients. In addition, it provides a comprehensive overview of currently available miRNAs associated with HNSCC and their extensive application for early diagnosis, prognosis, and treatment. Scientists and clinicians looking to win the battle against HNSCC will benefit from the book's sections on early diagnosis to improve treatment, increase treatment response rates, and reduce mortality rates. Recently, miRNA-based diagnostics and therapeutics have gained considerable attention among the scientific community. MiRNAs are known to have great potential as biomarkers for early diagnosis, prediction, and prognosis of HNSCC, and play a role in development of targeted gene therapy.

CAC series highlights new advances in the field. This Volume 94 presents interesting chapters on the recent advances in the role of nanoparticles in plant biotechnology. Each chapter is written by international experts in the respective fields.

Nanomaterials for Biocatalysis explains the fundamental design concepts and emerging applications of nanoscale biocatalysts, such as bioconversions, bioelectronics, biosensors, biocomputing and therapeutic applications. Nano-biocatalysts refers to the incorporation of enzymes into nanomaterials. These enzyme-enhanced nanocarriers have many advantages, including low mass transfer limitation, high enzyme capacity, better stabilization, and the formation of single-enzyme nanoparticles. Smart nanocontainers have been developed for the smart release of their embedded active substances. These smart releases can be obtained by using smart coatings as their outer nanoshells. In addition, these nanocontainers could protect the enzymes from chemical or metabolic alterations on their delivering pathways towards the target. This is an important reference source for materials scientists and chemical engineers who want to know more about how nanomaterials are being used for biocatalysis applications.

Biopolymeric Nanomaterials: Fundamentals and Applications outlines the fundamental design concepts and emerging applications of biopolymeric nanomaterials. The book also provides information on emerging applications of biopolymeric nanomaterials, including in biomedicine, manufacturing and water purification, as well as assessing their physical, chemical and biological properties. This is an important reference source for materials scientists, engineers and biomedical scientists who are seeking to increase their understanding of how polymeric nanomaterials are being used for a range of biomedical and industrial applications. Biopolymeric nanomaterials refer to biocompatible nanomaterials, consisting of biopolymers, such as protein (silk, collagen, gelatin, ss-casein, zein, and albumin), protein-mimicked polypeptides and polysaccharides (chitosan, alginate, pullulan, starch, and heparin). Biopolymeric nanomaterials may be used as i) delivery systems for bioactive compounds in food application, (ii) for delivery of therapeutic molecules (drugs and genes), or for (iii) tissue engineering.

The depletion of fossil fuels is a major issue in energy generation; hence, biomass and renewable energy sources, especially bioenergy, are the solution. The dependence on bioenergy has many benefits to mitigate environmental pollution. It is imperative that the global society adopts these alternative, sustainable energy sources in order to mitigate the constant growth of climate change. Biomass and Bioenergy Solutions for Climate Change Mitigation and Sustainability highlights the challenges of energy conservation and current scenarios of existing fossil fuel uses along with pollution potential of burning fossil fuel. It further promotes the inventory, assessment, and use of biomass, pollution control, and techniques. This book provides the solution for climate change, mitigation, and sustainability. Covering topics such as biofuel policies, economic considerations, and microalgae biofuels, this premier reference source is an essential resource for environmental scientists, environmental engineers, government officials, business leaders, politicians, librarians, students and faculty of higher education, researchers, and academicians.

In recent years, epidemiological studies have shown a significant increase of incidences regarding ulcerative colitis (UC) in most regions of the world. At present, a common therapeutic modality for inflammatory bowel disorders is the use of anti-inflammatory agents, including sulfasalazine and acetylsalicylic acid, steroid hormone, and other immunosuppressive agents. Most of these treatments are symptomatic and palliative because the etiology of the disease is not yet established. As a result of no proper drug available to treat UC, patients with UC are at a high risk of developing colitis-associated cancer (CAC). It is necessary to understand the genetic and molecular mechanisms involved in the pathogenesis of UC and CAC that lead to the path of new drug discoveries. Diagnostic and Treatment Methods for Ulcerative Colitis and Colitis-Associated Cancer provides innovative insights that describe the fundamental understanding of UC and CAC and the molecular mechanisms behind the etiology as well as modern diagnostic methods that are employed in UC and CAC. Current prevention and therapeutic strategies practiced in the pre-clinical level are also discussed. The content within this publication examines alternative medicine and dietary intervention and drug delivery techniques. It is designed for healthcare professionals, physicians, academicians, researchers, R&D organizations, and medical students involved in drug discovery and clinical and therapeutic research.

Improving Cereal Productivity through Climate Smart Practices is based on the presentations of the 4th International Group Meeting on "Wheat productivity enhancement through climate smart practices," and moves beyond the presentations to provide additional depth and breadth on this important topic. Focused specifically on wheat, and with chapters contributed by globally renowned pioneers in the field of cereal science, the book helps readers understand climate change and its effects on different aspects of wheat production in different parts of the world. This book will be important for those in research and industry seeking to contribute to the effective feeding of the world's population.

Many natural products are known to have health-promoting pharmaceutical activities. For example, capsaicin, curcumin, epigallocatechin, resveratrol, and quercetin have been reported to possess anti-inflammatory activity. Additionally, bioactive agents such as flavonoids, alkaloids, and terpenoids have shown a protective effect against diseases such as cancer, liver diseases, cardiovascular diseases, neurological disorders, diabetes mellitus, and more. Pharmacological Benefits of Natural Agents compiles the beneficial effects of bioactive natural agents with reference to many disease conditions and considers the challenges and future directions for their use. Covering key topics such as cancer, pharmaceutical activities, bioactive compounds, and treatments, this reference work is ideal for medical professionals, pharmacists, biologists, policymakers, researchers, scholars, practitioners, academicians, instructors, and students.

Analysis, Fate, and Toxicity of Engineered Nanomaterials in Plants, Volume 84 in the Comprehensive Analytical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters on the Current status of environmental monitoring, Physical principles of infrared, Chemical principles of infrared, Instrumentation and hardware, Data analysis, Sampling, Applications in water, Application in soil and sediments, Applications in ecology of animals and plants, Applications in air monitoring, Applications in contamination, Applications in marine environments, Advantages and pitfalls, and more.

Many chemotherapeutic agents are available in today's market that are highly effective against a variety of cancer types; however, the major drawbacks of these chemotherapeutic agents are the many side effects. As an alternative to these chemotherapeutic agents, there are a number of natural agents that are effective against cancer that have been tested in preclinical and clinical models over the years. These natural products must be documented and discussed in order to provide a thorough overview of all the options available for cancer treatment. The Handbook of Research on Natural Products and Their Bioactive Compounds as Cancer Therapeutics emphasizes the list of natural agents against all types of cancers and discusses the current state of research in the fields of natural products and their derivatives against cancer in preclinical and clinical models. This book also provides insight into the applications of meditation and mindfulness-based interventions in clinical and non-clinical conditions. Covering topics such as cancer therapy, antioxidants, and flavonoids, it is ideal for students, research scholars, academicians, professors, scientists, oncologists, doctors, and medical practitioners.

Computational Approaches for Novel Therapeutic and Diagnostic Designing to Mitigate SARS-CoV2 Infection: Revolutionary Strategies to Combat Pandemics compiles information about various computational bioinformatic approaches that can help combat viral infection. The book includes working knowledge of various molecular docking and molecular dynamic simulation approaches that have been exploited for drug repurposing and drug designing purpose. In addition, it sheds light on reverse vaccinomics and immunoinformatic approaches for vaccine designing against SARS-CoV2 infection. This book is an essential resource for researchers, bioinformaticians, computational biologists, computational chemists and pharmaceutical companies who are working on the development of effective and specific therapeutic interventions and point-of-care diagnostic devices using various computational approaches.

Availability of good books written by Indian author on management of 'Human Resource' in organization level is very limited. Book written by foreign author mainly dealt with situations faced in working climate of foreign countries which are quite different than Indian working condition. In this context, it is felt necessary to publish a book on 'Human Resource Development' which will be helpful to all HR professionals and Management students as a reference book. It is constituted with thirteen important s written by twelve experts working on HR in different establishments. I have taken the opportunity to compile those s together. All the topics are very essential for persons dealing HR activities to improve knowledge, to bring attitudinal change and to develop welfare mind, resulting ultimate benefit to employees as well as institutes.