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The book contains contributions concerning the application of
the new instrumental and methodological developments in omics
technologies, including those related to Genomics, Transcriptomics,
Proteomics, Peptidomics and Metabolomics, Lipidomics and Foodomics.
The16 chapters discuss in detail: innovative applications of
functional gene microarrays for profiling microbial communities,
microRNA profiling, novel genotyping applications using microarray
technology in cancer research, next-generation sequencing applied
to the study of human microbiome, emerging RNA-SEQ applications in
food science, recent progress in plant proteomics, applications of
gel-free proteomic approaches, the challenges and applications of
proteomics tools for food authenticity, the role of salivary
peptidomics in clinical applications, metabolomic approaches to the
study of degenerative, cardiovascular and renal diseases, and
neonatal medicine. Also covered are other omics applications such
as profiling of genetically modified organisms, the fundamentals,
applications and challenges of foodomics, and MS-based lipidomics.
Moreover, this volume includes relevant and updated aspects on
bioinformatics, data treatment, data integration and systems
biology. This book complements the previous volume "Fundamentals of
Advanced Omics Technologies: New Advances from Genes to
Metabolites" that covered the fundamental aspects of these new
omics technologies.
"Fundamentals of Advanced Omics Technologies: From Genes to Metabolites" covers the fundamental aspects of the new instrumental and methodological developments in omics technologies, including those related to genomics, transcriptomics, epigenetics, proteomics and metabolomics, as well as other omics approaches such as glycomics, peptidomics and foodomics. The principal applications are presented in the following complementary volume. The chapters discuss in detail omics technologies, DNA
microarray analysis, next-generation sequencing technologies,
genome-wide analysis of methylation and histone modifications,
emerging nanotechniques in proteomics, imaging mass spectrometry in
proteomics, recent quantitative proteomics approaches, and advances
in high-resolution NMR-based metabolomics, as well as MS-based
non-targeted metabolomics and metabolome analysis by CE-MS, global
glycomics analyses, foodomics, and high resolution analytical tools
for quantitative peptidomics. Key aspects related to chemometrics,
bioinformatics, data treatment, data integration and systems
biology, deep-sequencing data analysis, statistical approaches for
the analysis of microarray data, the integration of transcriptome
and metabolome data and computational approaches for visualization
and integration of omics data are also covered.
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