"Fundamentals of Advanced Omics Technologies: From Genes to
Metabolites" covers the fundamental aspects of the new instrumental
and methodological developments in omics technologies, including
those related to genomics, transcriptomics, epigenetics, proteomics
and metabolomics, as well as other omics approaches such as
glycomics, peptidomics and foodomics. The principal applications
are presented in the following complementary volume.
The chapters discuss in detail omics technologies, DNA
microarray analysis, next-generation sequencing technologies,
genome-wide analysis of methylation and histone modifications,
emerging nanotechniques in proteomics, imaging mass spectrometry in
proteomics, recent quantitative proteomics approaches, and advances
in high-resolution NMR-based metabolomics, as well as MS-based
non-targeted metabolomics and metabolome analysis by CE-MS, global
glycomics analyses, foodomics, and high resolution analytical tools
for quantitative peptidomics. Key aspects related to chemometrics,
bioinformatics, data treatment, data integration and systems
biology, deep-sequencing data analysis, statistical approaches for
the analysis of microarray data, the integration of transcriptome
and metabolome data and computational approaches for visualization
and integration of omics data are also covered.
Covers the latest advances in instrumentation, experimental design,
sample preparation, and data analysisProvides thorough explanations
and descriptions of specific omics technologiesDescribes advanced
tools and methodologies for data pretreatment, storage, curation
and analysis, as well as data integration
General
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