Drawing together the most up-to-date research from experts all across the world, the second edition of Computer Science Education offers the most up-to-date coverage available on this developing subject, ideal for building confidence of new pre-service and in-service educators teaching a new discipline. It provides an international overview of key concepts, pedagogical approaches and assessment practices. Highlights of the second edition include: - New sections on machine learning and data-driven (epistemic) programming - A new focus on equity and inclusion in computer science education - Chapters updated throughout, including a revised chapter on relating ethical and societal aspects to knowledge-rich aspects of computer science education - A new set of chapters on the learning of programming, including design, pedagogy and misconceptions - A chapter on the way we use language in the computer science classroom. The book is structured to support the reader with chapter outlines, synopses and key points. Explanations of key concepts, real-life examples and reflective points keep the theory grounded in classroom practice. The book is accompanied by a companion website, including online summaries for each chapter, 3-minute video summaries by each author and an archived chapter on taxonomies and competencies from the first edition.

Improving Computer Science Education examines suitable theoretical frameworks for conceptualizing teaching and learning computer science. This highly useful book provides numerous examples of practical, "real world" applications of major computer science information topics, such as:

Spreadsheets
Databases
Programming

Each chapter concludes with a section that summarzies recommendations for teacher professional development. Traditionally, computer science education has been skills-focused and disconnected from the reality students face after they leave the classroom. Improving Computer Science Education makes the subject matter useful and meaningful by connecting it explicitly to students' everyday lives.

Optical probes, particularly the fluorescent varieties, enable researchers to observe cellular events in real time and with great spatial resolution. Optical Probes in Biology explores the diverse capabilities of these powerful and versatile tools and presents various approaches used to design, develop, and implement them. The book examines the use of optical probes to detect and track numerous molecular processes in living cells, including GTPase and kinase activities, membrane lipids, voltage, metal ions, metabolic signals, RNA, and histone modifications. It critically reviews the different probe designs and delves into the strategies for developing new fluorescent protein varieties with enhanced capabilities. It also covers sophisticated imaging techniques and equipment, such as intensity and lifetime-based fluorescence microscopy methods, used to visualize and track optical probes. In addition, the book goes beyond live-cell tracking to discuss the growing application of activity-based probes for performing pharmacological drug screening and probing molecular processes in living animals. It also discusses emerging techniques that are expanding optical probe-based approaches into new biological frontiers. With contributions from top international scientists, this book offers a thorough overview of the latest optical probes in cell biology and biochemistry. Both newcomers and established researchers will discover how to incorporate state-of-the-art optical probes and fluorescence imaging into their research.

Defects in Secretion of Cystic Fibrosis presents an overview on current research from leading experts in North America and Europe. This update on cystic fibrosis provides in depth original work as well as review material on many of the relevant physiological and molecular topics in the field. Subjects covered include the interplay of the various epithelial ion channels, the underlying intracellular signal transduction, mucus secretion, and novel approaches to develop drugs against cystic fibrosis. This book brings together physicians, physiologists, and other scientists involved in basic research, from molecular biology to drug design and introduces novel investigative and therapeutic aspects of secretion disorders relevant in cystic fibrosis and related diseases.

This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases.

Improving Computer Science Education examines suitable theoretical frameworks for conceptualizing teaching and learning computer science. This highly useful book provides numerous examples of practical, "real world" applications of major computer science information topics, such as: * Spreadsheets * Databases * Programming Each chapter concludes with a section that summarzies recommendations for teacher professional development. Traditionally, computer science education has been skills-focused and disconnected from the reality students face after they leave the classroom. Improving Computer Science Education makes the subject matter useful and meaningful by connecting it explicitly to students' everyday lives.

Diese Schrift erscheint zu Ehren von Prof. Dr. Dr. h.c. Hans Georg Gemunden (TU Berlin). Die betriebswirtschaftliche Innovationsforschung befahigt Unternehmen, erfolgreich Innovationen zu initiieren, Innovationsprojekte durchzufuhren und neue Produkte und Dienstleistungen in den Markt einzufuhren. Es werden Anforderungen an die strategischen, organisatorischen und kulturellen Rahmenbedingungen abgeleitet und unternehmensinterne und -externe Motoren der Innovation aufgezeigt. Unternehmensintern wird die Rolle des Menschen, unnternehmensextern wird die Einbindung von Wertschoepfungspartnern und Kunden im Innovationsprozess betont. Einer der herausragenden Protagonisten in vielen dieser Themengebiete ist Prof. Gemunden. Die Beitragsautoren gehen der Frage nach, wie sich die Anforderungen an das Innovationsmanagement in Zukunft andern und welche Zukunftsperspektiven sich daraus fur die Praxis und Forschung eroeffnen.

Optical probes, particularly the fluorescent varieties, enable researchers to observe cellular events in real time and with great spatial resolution. Optical Probes in Biology explores the diverse capabilities of these powerful and versatile tools and presents various approaches used to design, develop, and implement them. The book examines the use of optical probes to detect and track numerous molecular processes in living cells, including GTPase and kinase activities, membrane lipids, voltage, metal ions, metabolic signals, RNA, and histone modifications. It critically reviews the different probe designs and delves into the strategies for developing new fluorescent protein varieties with enhanced capabilities. It also covers sophisticated imaging techniques and equipment, such as intensity and lifetime-based fluorescence microscopy methods, used to visualize and track optical probes. In addition, the book goes beyond live-cell tracking to discuss the growing application of activity-based probes for performing pharmacological drug screening and probing molecular processes in living animals. It also discusses emerging techniques that are expanding optical probe-based approaches into new biological frontiers. With contributions from top international scientists, this book offers a thorough overview of the latest optical probes in cell biology and biochemistry. Both newcomers and established researchers will discover how to incorporate state-of-the-art optical probes and fluorescence imaging into their research.

Carsten Schultz befragt Patienten, Arzte und Krankenkassen und zeigt, dass Kunden dann wertvolle Beitrage zur Entwicklung und Markteinfuhrung innovativer Dienstleistungen erbringen, wenn sie eng an den Anbieter gebunden sind. Dazu mussen Unternehmen bestehende Informationsdefizite beim Kunden abbauen. Abschliessend werden Unterschiede in den Beziehungen zu End- bzw. Geschaftskunden systematisch abgeleitet.

Drawing together the most up-to-date research from experts all across the world, the second edition of Computer Science Education offers the most up-to-date coverage available on this developing subject, ideal for building confidence of new pre-service and in-service educators teaching a new discipline. It provides an international overview of key concepts, pedagogical approaches and assessment practices. Highlights of the second edition include: - New sections on machine learning and data-driven (epistemic) programming - A new focus on equity and inclusion in computer science education - Chapters updated throughout, including a revised chapter on relating ethical and societal aspects to knowledge-rich aspects of computer science education - A new set of chapters on the learning of programming, including design, pedagogy and misconceptions - A chapter on the way we use language in the computer science classroom. The book is structured to support the reader with chapter outlines, synopses and key points. Explanations of key concepts, real-life examples and reflective points keep the theory grounded in classroom practice. The book is accompanied by a companion website, including online summaries for each chapter, 3-minute video summaries by each author and an archived chapter on taxonomies and competencies from the first edition.

Integrierte Versorgungsnetzwerke und Medizinische Versorgungszentren (MVZ) als Ansatze, die intersektorale und interdisziplinare Zusammenarbeit zwischen medizinischen Akteuren zu verbessern, konnen zur Zukunftssicherung des Gesundheitswesens nachhaltig beitragen. Sie bedingen aufgrund ihrer Komplexitat ein systematisches Management unter Ausnutzung der Moglichkeiten moderner informationstechnischer Instrumente.Das Werk setzt sich mit dem IT-basierten Management solcher innovativer Versorgungsformen im Gesundheitswesen auseinander. Auf einer breiten empirischen Basis und aus interdisziplinarer Sicht ermittelt es managementbezogene Probleme, stellt zentrale Erfolgsfaktoren dar und leitet praxisgerecht die Aufgaben fur ein systematisches Management ab. Erfahrungen aus der Praxis vervollstandigen die Darstellung.