This book constitutes the refereed proceedings of the Second NSF Workshop on Biosurveillance Systems and Case Studies, BioSurveillance 2007, held in New Brunswick, NJ, USA in May 2007, co-located with the 2007 IEEE International Conference on Intelligence and Security Informatics (ISI 2007).

The 17 revised full papers, 6 revised short papers presented together with 1 invited talk and 2 poster papers were carefully reviewed and selected for inclusion in the book. Bringing together infectious disease informatics (IDI) researchers and practitioners to discuss selected topics directly relevant to data sharing and analysis for real-time animal and public health surveillance, the workshop covers a wide range of backgrounds such as epidemiology, statistics, applied mathematics, information systems, computer science and machine learning/data mining.