0
Your cart

Your cart is empty

Browse All Departments
  • All Departments
Price
  • R2,500 - R5,000 (2)
  • -
Status
Brand

Showing 1 - 2 of 2 matches in All Departments

Nanoscale Imaging and Characterisation of Amyloid- (Hardcover, 1st ed. 2016): Claire Louisa Tinker-Mill Nanoscale Imaging and Characterisation of Amyloid- (Hardcover, 1st ed. 2016)
Claire Louisa Tinker-Mill
R3,467 Discovery Miles 34 670 Ships in 12 - 19 working days

This thesis presents a method for reliably and robustly producing samples of amyloid- (A ) by capturing them at various stages of aggregation, as well as the results of subsequent imaging with various atomic force microscopy (AFM) methods, all of which add value to the data gathered by collecting information on the peptide's nanomechanical, elastic, thermal or spectroscopical properties. Amyloid- (A ) undergoes a hierarchy of aggregation following a structural transition, making it an ideal subject of study using scanning probe microscopy (SPM), dynamic light scattering (DLS) and other physical techniques. By imaging samples of A with Ultrasonic Force Microscopy, a detailed substructure to the morphology is revealed, which correlates well with the most advanced cryo-EM work. Early stage work in the area of thermal and spectroscopical AFM is also presented, and indicates the promise these techniques may hold for imaging sensitive and complex biological materials. This thesis demonstrates that physical techniques can be highly complementary when studying the aggregation of amyloid peptides, and allow the detection of subtle differences in their aggregation processes.

Nanoscale Imaging and Characterisation of Amyloid- (Paperback, Softcover reprint of the original 1st ed. 2016): Claire Louisa... Nanoscale Imaging and Characterisation of Amyloid- (Paperback, Softcover reprint of the original 1st ed. 2016)
Claire Louisa Tinker-Mill
R3,315 Discovery Miles 33 150 Ships in 10 - 15 working days

This thesis presents a method for reliably and robustly producing samples of amyloid- (A ) by capturing them at various stages of aggregation, as well as the results of subsequent imaging with various atomic force microscopy (AFM) methods, all of which add value to the data gathered by collecting information on the peptide's nanomechanical, elastic, thermal or spectroscopical properties. Amyloid- (A ) undergoes a hierarchy of aggregation following a structural transition, making it an ideal subject of study using scanning probe microscopy (SPM), dynamic light scattering (DLS) and other physical techniques. By imaging samples of A with Ultrasonic Force Microscopy, a detailed substructure to the morphology is revealed, which correlates well with the most advanced cryo-EM work. Early stage work in the area of thermal and spectroscopical AFM is also presented, and indicates the promise these techniques may hold for imaging sensitive and complex biological materials. This thesis demonstrates that physical techniques can be highly complementary when studying the aggregation of amyloid peptides, and allow the detection of subtle differences in their aggregation processes.

Free Delivery
Pinterest Twitter Facebook Google+
You may like...
Shark Quest
Paperback R74 Discovery Miles 740
Into A Raging Sea - Great South African…
Tony Weaver, Andrew Ingram Paperback  (2)
R579 Discovery Miles 5 790
ABC to VEG
Natasha Michaud Hardcover R514 Discovery Miles 5 140
Disaster Management: Challenges and…
Cathy Hogan Hardcover R3,229 R2,921 Discovery Miles 29 210
Sucker-Rod Pumping Handbook - Production…
Gabor Takacs Paperback R2,662 Discovery Miles 26 620
Band Of Brothers
Stephen E. Ambrose Paperback  (2)
R270 R241 Discovery Miles 2 410
Grid Optimal Integration of Electric…
Andres Ovalle, Ahmad Hably, … Hardcover R3,395 Discovery Miles 33 950
Physics, Formation and Evolution of…
Andre Maeder Hardcover R5,682 Discovery Miles 56 820
Miss Behave
Malebo Sephodi Paperback  (12)
R302 Discovery Miles 3 020
Sudden Sea - The Great Hurricane of 1938
R. A Scotti Paperback R491 R458 Discovery Miles 4 580

 

Partners