This issue of Medical Clinics of North America, guest edited by Drs. David A. Sass and Alden M. Doyl, is devoted to Care of the Liver and Kidney Transplant Recipient. Articles in this issue include: Liver and kidney transplantation: a half-century historical perspective; From Child's-Pugh to MELD: Deciding who really needs a liver transplant; When to consider renal transplantation in your advanced CKD patients; Management of the liver transplant recipient: approach to allograft dysfunction; Acute and chronic allograft dysfunction in renal transplant recipients; The ABC's of Immunosuppression: a primer for the primary care physician; Managing cardiovascular risk in the post solid organ transplant recipient; Diabetes care after transplant: definitions, risk factors, and clinical management; De novo malignancies after transplantation: risk and surveillance strategies; Metabolic bone disease in the post-transplant population: preventative and therapeutic measures; Infectious complications and vaccinations in the post-transplant population; Selection and post-operative care of the living donor; and Long-term functional recovery, quality of life and pregnancy following solid organ transplantation.

This issue will provide gastroenterologists with the most current information on clinical matters in hepatology and serves as an update to the last issue. Articles address the spectrum of matters involving the liver, including Hepatitis C, Hepatitis B, alcoholic Hepatitis, hemochromatosis, varices, liver transplantation, non-alcoholic fatty liver disease, liver failure, and hepatic fibrosis.

This issue of the Medical Clinics of North America brings the practicing clinician up to date on best practices of caring for the cirrhotic patient. Topics covered include diagnosis and epidemiology of cirrhosis; ascites: diagnosis and management; encephalopathy: pathophysiology and emerging therapies; portal hypertensive bleeding; renal failure: differential diagnosis and management; pulmonary complications; hepatocellular carcinoma: current state of treatment; preventative health issues; pre-operative risk assessment; and liver transplantation: from Child's to MELD.