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Food security, crop protection, biodiversity, and human and
environmental health are among the main needs and concerns of
society. Modern biotechnology and life sciences represent a
constantly evolving area that is key for the rational use of
natural resources - resources that in turn are indispensable for
societal development. This book features the outcomes of the IV
International Biotechnology and Biodiversity Congress, held in
Guayaquil, Ecuador, 2018. It includes extensive reviews of the
trends in agricultural and forestry biotechnology, molecules and
materials biodiscovery, ethnomedicine, environmental impact and
bioindustry research, describing many of these topics from the
Latin America perspective and showing how the biodiversity and
ancient knowledge of these countries are vital for worldwide
sustainable development.
Chemical Biology of Natural Products This unique, long-awaited
volume is designed to address contemporary aspects of natural
product chemistry and its influence on biological systems, not
solely on human interactions. The subjects covered include
discovery, isolation and characterization, biosynthesis,
biosynthetic engineering, pharmaceutical, and other applications of
these compounds. Each chapter begins with a brief and simple
introduction to the subject matter, and then proceeds to guide the
reader towards the more contemporary, cutting-edge research in the
field, with the contributing authors presenting current examples
from their own work in order to exemplify key themes. Topics
covered in the text include genome mining, heterologous expression,
natural product synthesis, biosynthesis, glycosylation, chemical
ecology, and therapeutic applications of natural products, both
current and potential.
The approach to drug discovery from natural sources has yielded
many important new pharmaceuticals inaccessible by other routes. In
many cases the isolated natural product may not be an effective
drug for any of several reasons, but it nevertheless may become a
drug through chemical modification or have a novel pharmacophore
for future drug design. In summarizing the status of natural
products as cancer chemotherapeutics, Anticancer Agents from
Natural Products, Second Edition covers the: History of each
covered drug-a discussion of its mechanism on action, medicinal
chemistry, synthesis, and clinical applications Potential for novel
drug discovery through the use of genome mining as well as future
developments in anticancer drug discovery Important biosynthetic
approaches to "unnatural" natural products Anticancer Agents from
Natural Products, Second Edition discusses how complex
target-oriented synthesis-enabled by historic advances in
methodology-has enormously expanded the scope of the possible. This
book covers the current clinically used anticancer agents that are
either natural products or are clearly derived from natural product
leads. It also reviews drug candidates currently in clinical
development since many of these will be clinically used drugs in
the future. Examples include the drugs etoposide and teniposide
derived from the lead compound podophyllotoxin; numerous analogs
derived from taxol; topotecan, derived from camptothecin; and the
synthetic clinical candidates, E7389 and HTI-286, developed from
the marine leads, halichondrin B and hemiasterlin.
Chemical Biology of Natural Products This unique, long-awaited
volume is designed to address contemporary aspects of natural
product chemistry and its influence on biological systems, not
solely on human interactions. The subjects covered include
discovery, isolation and characterization, biosynthesis,
biosynthetic engineering, pharmaceutical, and other applications of
these compounds. Each chapter begins with a brief and simple
introduction to the subject matter, and then proceeds to guide the
reader towards the more contemporary, cutting-edge research in the
field, with the contributing authors presenting current examples
from their own work in order to exemplify key themes. Topics
covered in the text include genome mining, heterologous expression,
natural product synthesis, biosynthesis, glycosylation, chemical
ecology, and therapeutic applications of natural products, both
current and potential.
Food security, crop protection, biodiversity, and human and
environmental health are among the main needs and concerns of
society. Modern biotechnology and life sciences represent a
constantly evolving area that is key for the rational use of
natural resources - resources that in turn are indispensable for
societal development. This book features the outcomes of the IV
International Biotechnology and Biodiversity Congress, held in
Guayaquil, Ecuador, 2018. It includes extensive reviews of the
trends in agricultural and forestry biotechnology, molecules and
materials biodiscovery, ethnomedicine, environmental impact and
bioindustry research, describing many of these topics from the
Latin America perspective and showing how the biodiversity and
ancient knowledge of these countries are vital for worldwide
sustainable development.
A discussion of the chemical compounds produced by organisms living
under extreme conditions that may have potential as drugs or leads
to novel drugs for human use. This SpringerBrief deals with
bioactive materials from terrestrial extremophiles.
Each chapter of this book aims to explore the basic physical and
chemical principles involved in the immunoassay techniques
discussed. The book also looks at the optimization and limitations
of methodology and concludes with a brief overview of the
application of the performance of the technology.
This SpringerBrief sheds new light on bioactive materials from
marine extremophiles. It deals with all aspects of the chemical
compounds produced by organisms living under extreme conditions
that may have potential as drugs or lead to novel drugs for human
use.
This SpringerBrief sheds new light on bioactive materials from
extremophiles with the focus on the biosynthesis processes and
related genomics. It deals with all aspects of the chemical
compounds produced by organisms living under extreme conditions
that may have potential as drugs or lead to novel drugs for human
use.
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Atmosfire
Jan Braai
Hardcover
R590
R425
Discovery Miles 4 250
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