The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.

This book provides an overview of crimes involving water, including pollution, illegal dumping, and supply chain disruption from a criminological perspective. It examines a multifaceted issue from a comparative policy perspective supplemented with individual case studies to provide insights on the magnitude of the problem as well as possible solutions and policy recommendations. As growing populations and economic sectors continue to put unprecedented pressures on water supplies, the book aims to contribute to a better understanding of the problem in order to ensure the sustainability, long-term viability, and equitable use of this essential resource. The first part of the volume examines criminological and policy perspectives, including an overview of regulatory approaches, privatization of water resources, and the scope of the criminal problem in this area. The second part presents informative case studies from a variety of different regional and social contexts. Finally, the editors present an outlook in policy and enforcement improvements. This work will be of interest to researchers in criminology, criminal justice, public policy, and comparative law, as well as those studying environmental regulations and sustainability. Water, Governance and Crime Issues is a much needed addition to the growing original contributions of green criminology. This volume captures the complex landscape of water crimes, including the numerous disparities and inequalities of there being too much water in some places and too little in others amongst the many complexities. The edited collection also covers conceptual issues (i.e. water as a human right) as well as practical hurdles (i.e. the challenges in keeping statistics on offences) and real world examples. Many of the chapters are likely to introduce readers to new issues and the interplay with a myriad of traditional problems - corruption, organised crime, privatisation, and terrorism. I agree with the editors and authors that water crime issues deserve further scientific study and this provides a solid starting point. -Dr. Tanya Wyatt, University of Northumbria Population growth and urbanization, more frequent droughts due to climate change, the privatization of and unequal access to water resources and increasing water pollution are just some of the contemporary and future challenges relating to water crimes. Water, Governance and Crime Issues speaks to the scientific relevance of water for (green) criminology as well as the policy implications of water crimes. Several of the cases in this edited book refer to countries and regions we do not usually hear about and yet are perfect illustrations of the challenges faced in governing and studying water crimes. -Dr. Lieselot Bisschop, Erasmus School of Law

This book presents emerging trends in the evolution of service-oriented and enterprise architectures. New architectures and methods of both business and IT are integrating services to support mobility systems, Internet of Things, Ubiquitous Computing, collaborative and adaptive business processes, Big Data, and Cloud ecosystems. They inspire current and future digital strategies and create new opportunities for the digital transformation of next digital products and services. Services Oriented Architectures (SOA) and Enterprise Architectures (EA) have emerged as a useful framework for developing interoperable, large-scale systems, typically implementing various standards, like Web Services, REST, and Microservices. Managing the adaptation and evolution of such systems presents a great challenge. Service-Oriented Architecture enables flexibility through loose coupling, both between the services themselves and between the IT organizations that manage them. Enterprises evolve continuously by transforming and extending their services, processes and information systems. Enterprise Architectures provide a holistic blueprint to help define the structure and operation of an organization with the goal of determining how an organization can most effectively achieve its objectives. The book proposes several approaches to address the challenges of the service-oriented evolution of digital enterprise and software architectures.

This book introduces readers to the tools needed to protect IT resources and communicate with security specialists when there is a security problem. The book covers a wide range of security topics including Cryptographic Technologies, Network Security, Security Management, Information Assurance, Security Applications, Computer Security, Hardware Security, and Biometrics and Forensics. It introduces the concepts, techniques, methods, approaches, and trends needed by security specialists to improve their security skills and capabilities. Further, it provides a glimpse into future directions where security techniques, policies, applications, and theories are headed. The book represents a collection of carefully selected and reviewed chapters written by diverse security experts in the listed fields and edited by prominent security researchers. Complementary slides are available for download on the book's website at Springer.com.

This book explores the multicultural and non-Western contexts behind the approaches, problems, and issues that arise in research methodologies when used in relation to educational administration and leadership. This volume argues that increasing internationalisation and diversity of the field requires research methods that better reflect the values, cultures, political systems, and conditions of non-Western communities and countries. Discussing the research methods, data collection practices, interpretive approaches and research ethics that produce more accurate and authentic results, the book looks at a number of theoretical frameworks and epistemological approaches that inform the development of such methodologies. Traditional methods like sharing circles and storytelling are explored, as well as an examination of 'social space' in designing methodology aimed at 'spatial justice' and an exploration of methods for Indigenous communities in East Asia. A valuable resource for researchers, scholars and students with an interest in multicultural education, the book will also appeal to academics interested in race, ethics, and educational research methods more broadly.

This comprehensive book discusses cartilage repair and all its aspects. These aspects vary from basic insights in cartilage biology and regeneration via MRI, to results of existing cartilage repair techniques and upcoming novel approaches. Fundamental cartilage biology is the topic covered within the first chapters of the book. These chapters not only provide an insight in healthy, damaged and regenerative cartilage but also describe developments in gene therapy and methods to enhance chondrogenesis of stemcells and prevent hypertophic differentiation. There is a huge progress in the possibilities of MR imaging of both healthy, damaged and regenerative cartilage. These developments not only enable better monitoring of cartilage repair but may also unravel the pathophysiology of the development of cartilage defects. Different cartilage repair techniques (e.g. allografts, autologous chondrocytes transplantation [ACT], microfracture), there technical aspects (e.g. developments towards an total arthroscopic approach), pitfalls, and outcomes are reported in the following chapters. In these chapters factors important for the results of cartilage repair such as meniscal repair, patient factors are described. Finally, an overview of novel cartilage repair techniques such as minced cartilage, denovo cartilage and more areas are discussed in this comprehensive addition to the literature.

Mad about marvellous vehicles? Hit the road with writer and broadcaster JAMES MAY to discover incredible human-powered vehicles – from bicycles and submarines to amphibious vehicles and even a helicopter. Yes, really! Our EXPERTS are famous for their incredible know-how and passion for their subjects, and now they have made it their mission to share that knowledge with you in LITTLE EXPERTS: the inspirational new non-fiction series for six- to nine-year-olds. This jaw-dropping non-fiction journey has bright, inclusive and stylish artwork throughout by Emans. Little Experts is an unmissable series that will empower and inspire a new generation of experts. Also available in the LITTLE EXPERTS series: Why Money Matters by DEBORAH MEADEN, entrepreneur, Dragon’s Den investor and host of the BBC Radio 5 Live’s The Big Green Money Show podcast. Amazing Bodies by DR RONX, award-winning trans non-binary emergency doctor and TV presenter.

Conducting a good interview is more difficult than one might imagine. Of course, thorough preparation is essential, but equally important are knowledge of the specific subject area and effective communication skills. Interviewing: Theory, Techniques and Training presents relevant theoretical perspectives, provides material to help develop a range of communication skills and describes tried and tested ways of preparing for interviews. There have been many developments in the field of interviewing in recent years. Computer-assisted protocols now play a prominent role in interviewing and there has been much research into the role of communication processes in interviews. Interviewing incorporates these recent developments and insights and offers up-to-date examples and practical suggestions.

This book explores the Islamic tradition and Muslim contexts for educational administration and leadership. It addresses the teaching of educational administration and leadership from an Islamic perspective by raising issues of globalised educational administration and leadership teaching as it applies in Muslim contexts that vary by culture and social institutions. The book proposes alternative approaches and demonstrates that Islamic traditions have a strong foundation upon which to build in the field and are compatible with many aspects of Western theory and practices, provided that sufficient modifications and adaptations are made. The book focuses on postgraduate curricula and pedagogy, drawing on a range of theoretical foundations and approaches that are culturally and jurisdictionally appropriate in a number of Muslim countries. As such, it contributes to an emerging specialisation in international and comparative educational administration and leadership that is oriented towards a broader and more diverse set of perspectives, particularly from the non-Western world.

The potential of adopting inclusive education to support learning for all is an international phenomenon that is finding its way to the Middle East and the Arabian region. Eman Gaad examines the current status of inclusive education in Arabia and the Middle East through an assessment of the latest international, regional, and local research into inclusive education. With a focus on the more complex areas of related cultural practice and attitudes towards inclusive education in this dynamic and fast-changing part of the world, Gaad offers a research-based analysis of the current educational status of the Arabian Gulf and some Middle Eastern countries that adopted inclusive practice in education, and others that are yet to follow. This book will be of great interest to students, academics, teachers, and therapists in the field of comparative and inclusive education as well as those with an interest in policies of education in the dynamic and culturally distinguished Middle Eastern Arabian region.