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Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Hardcover, 2006 ed.): Eric Verdin Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Hardcover, 2006 ed.)
Eric Verdin
R5,490 Discovery Miles 54 900 Ships in 10 - 15 working days

A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Paperback, Softcover reprint of hardcover 1st... Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Paperback, Softcover reprint of hardcover 1st ed. 2006)
Eric Verdin
R5,456 Discovery Miles 54 560 Ships in 10 - 15 working days

A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

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