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Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology
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Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Hardcover, 2006 ed.)
Loot Price: R5,490
Discovery Miles 54 900
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Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Hardcover, 2006 ed.)
Series: Cancer Drug Discovery and Development
Expected to ship within 10 - 15 working days
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A panel of leading investigators summarizes and synthesizes the new
discoveries in the rapidly evolving field of histone acetylation as
a key regulatory mechanism for gene expression. The authors
describe what has been learned about these proteins, including the
identification of the enzymes, the elucidation of the enzymatic
mechanisms of action, and the identification of their substrates
and their partners. They also review the structures that have been
solved for a number of enzymes-both alone and in complex with small
molecule inhibitors-and the biological roles of the several histone
deacetylases (HDAC) genes that have been knocked out in mice.
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