Histone Deacetylases - Transcriptional Regulation and Other Cellular Functions (Hardcover, 2006 ed.)

A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Cancer Drug Discovery and Development
Release date:	2006
First published:	2006
Editors:	Eric Verdin
Dimensions:	235 x 155 x 25mm (L x W x T)
Format:	Hardcover
Pages:	352
Edition:	2006 ed.
ISBN-13:	978-1-58829-499-9
Categories:	Books > Medicine > General issues > Medical equipment & techniques > Medical research Books > Medicine > Pre-clinical medicine: basic sciences > Physiology > Cellular physiology Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-58829-499-4
Barcode:	9781588294999

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