This book describes the most frequently used high-speed serial buses in embedded systems, especially those used by FPGAs. These buses employ SerDes, JESD204, SRIO, PCIE, Aurora and SATA protocols for chip-to-chip and board-to-board communication, and CPCIE, VPX, FC and Infiniband protocols for inter-chassis communication. For each type, the book provides the bus history and version info, while also assessing its advantages and limitations. Furthermore, it offers a detailed guide to implementing these buses in FPGA design, from the physical layer and link synchronization to the frame format and application command. Given its scope, the book offers a valuable resource for researchers, R&D engineers and graduate students in computer science or electronics who wish to learn the protocol principles, structures and applications of high-speed serial buses.

This book is open access under a CC BY 4.0 license. CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease. This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.

Over the past 50 years, biotechnology has been the major driving force for increasing crop productivity. Particularly, advances in plant genetic engineering technologies have opened up vast new opportunities for plant researchers and breeders to create new crop varieties with desirable traits. Recent development of precise genome modification methods, such as targeted gene knock-out/knock-in and precise gene replacement, moves genetic engineering to another level and offers even more potentials for improving crop production. The work provides an overview of the latest advances on precise genomic engineering technologies in plants. Topics include recombinase and engineered nucleases-mediated targeted modification, negative/positive selection-based homologous recombination and oligo nucleotide-mediated recombination. Finally, challenges and impacts of the new technologies on present regulations for genetic modification organisms (GMOs) will be discussed.

This volume explores the implications of pluralism for international order. Distinguished contributors from around the world offer insights into the character of a pluralistic world order. They focus especially on the manifestations of international pluralism in great power relations, multilateralism, and regionalism. Contributors examine the myriad challenges a pluralistic world order will face in the years ahead, yet they eschew alarmist conclusions. There is still scope for the great powers to better manage their relations, and equally important, much space for multilateralism and regionalism to play their increasingly important roles in stabilizing world order. Distinctive in bringing the themes of pluralism and world order together in both theoretical exposition and policy discussion, this book offers a stimulating reading for scholars and practitioners of world politics.

Competition between America and China has intensified since 2009, creating even greater risks of conflict. Why is this so and what can be done about it? In Taming Sino-American Rivalry, Feng Zhang and Richard Ned Lebow reject the prevailing idea that competition between a dominant and a rising power must necessarily lead to conflict. Rather, they identify the mistakes that both countries have made and explain the causes and consequences of their missteps. Drawing on international relations theory and lessons from history, they develop a comprehensive approach to conflict management and resolution that balances deterrence, reassurance, and diplomacy. A challenge to the prevailing pessimism, Taming Sino-American Rivalry is essential reading for anyone interested in understanding the world's most important bilateral relationship.

This detailed volume collects protocols from scientists who are actively engaged in developing or using protoplast technology. The book begins with chapters that focus on basic protoplast techniques and their utilities, such as protocols on protoplast isolation, transfection, and regeneration, as well as examples of how to use protoplasts for genome editing and gene function analysis in a number of major crop or model plant species. It continues by exploring protoplast automation, large scale functional genomics, and synthetic biology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Protoplast Technology: Methods and Protocols aims to inspire the new generation of researchers to further improve their protocols and apply this technology to accelerate the field of plant genomic study.

With the rapid development and drastic change of the world economy, "Digital Finance", "Internet Finance", "Science and Technology Finance" have become new hotspots, which also represent the future trend of economy development in the era of big data. Enterprises are facing more uncertainty, opportunities coexist with challenges. There are more possibilities for economic development and enterprise management to accelerate the integration of cutting-edge research results, to deepen hot topics discussion and to promote opinion exchanges among academic and business circles. The Sixth International Conference on Economic and Business Management (FEBM2021) was successfully held online on October 16-17, 2021, and aimed to provide a platform for researchers, engineers, academics as well as industry professionals from all over the world to present their latest research findings and development activities in economic and business management. These proceedings include 51 accepted articles selected from 94 submissions.

This book systematically introduces physical characteristics and implementations of III-nitride wide bandgap semiconductor materials and electronic devices, with an emphasis on high-electron-mobility transistors (HEMTs). The properties of nitride semiconductors make the material very suitable for electronic devices used in microwave power amplification, high-voltage switches, and high-speed digital integrated circuits.

This book systematically introduces physical characteristics and implementations of III-nitride wide bandgap semiconductor materials and electronic devices, with an emphasis on high-electron-mobility transistors (HEMTs). The properties of nitride semiconductors make the material very suitable for electronic devices used in microwave power amplification, high-voltage switches, and high-speed digital integrated circuits.

The first edition of Pharmaceutical Extrusion Technology, published in 2003, was deemed the seminal book on pharmaceutical extrusion. Now it is expanded and improved, just like the usage of extrusion has expanded, improved and evolved into an accepted manufacturing technology to continuously mix active pharmaceutical ingredients with excipients for a myriad of traditional and novel dosage forms. Pharmaceutical Extrusion Technology, Second Edition reflects how this has spawned numerous research activities, in addition to hardware and process advancements. It offers new authors, expanded chapters and contains all the extrusion related technical information necessary for the development, manufacturing, and marketing of pharmaceutical dosage forms. Key Features: Reviews how extrusion has become an accepted technology to continuously mix active pharmaceutical ingredients with excipients Focuses on equipment and process technology Explains various extrusion system configurations as a manufacturing methodology for a variety of dosage forms Presents new opportunities available only via extrusion and future trends Includes contributions of experts from the process and equipment fields

A comparative exploration of Western and Chinese understandings of justice and their possible use to reframe Sino-American relations and international governance. The concept of justice is central to politics: it justifies the ordering of society and the distribution of rewards. In Justice and International Order, Richard Ned Lebow and Feng Zhang compare and contrast Western and Chinese conceptions of justice. They argue that justice can almost invariably be reduced to the principles of fairness and equality, although they are developed and expressed differently in the two cultures. Lebow and Zhang show that there has been a noticeable shift in both in favoring equality over fairness in the modern era. They analyze the growing conflict between China and the West in the light of these conceptions of justice and show how they might be deployed to ameliorate it. The authors also offer a critique of what passes for global order and explore ways in which fairness and equality, and trade-offs between them, offer pathways to better and more peaceful worlds.

The first edition of Pharmaceutical Extrusion Technology, published in 2003, was deemed the seminal book on pharmaceutical extrusion. Now it is expanded and improved, just like the usage of extrusion has expanded, improved and evolved into an accepted manufacturing technology to continuously mix active pharmaceutical ingredients with excipients for a myriad of traditional and novel dosage forms. Pharmaceutical Extrusion Technology, Second Edition reflects how this has spawned numerous research activities, in addition to hardware and process advancements. It offers new authors, expanded chapters and contains all the extrusion related technical information necessary for the development, manufacturing, and marketing of pharmaceutical dosage forms. Key Features: Reviews how extrusion has become an accepted technology to continuously mix active pharmaceutical ingredients with excipients Focuses on equipment and process technology Explains various extrusion system configurations as a manufacturing methodology for a variety of dosage forms Presents new opportunities available only via extrusion and future trends Includes contributions of experts from the process and equipment fields

Communication of risks within a transparent and accountable framework is essential in view of increasing mobility and the complexity of the modern society and the field of geotechnical engineering does not form an exception. As a result, modern risk assessment and management are required in all aspects of geotechnical issues, such as planning, design, construction of geotechnical structures, mitigation of geo-hazards, management of large construction projects, maintenance of structures and life-cycle cost evaluation. This volume discusses: 1. Evaluation and control of uncertainties through investigation, design and construction of geotechnical structures; 2. Performance-based specifications, reliability based design and limit state design of geotechnical structures, and design code developments; 3. Risk assessment and management of geo-hazards, such as landslides, earthquakes, debris flow, etc.; 4. Risk management issues concerning large geotechnical construction projects; 5. Repair and maintenance strategies of geotechnical structures. Intended for researchers and practitioners in geotechnical, geological, infrastructure and construction engineering.

Chinese Hegemony: Grand Strategy and International Institutions in East Asian History joins a rapidly growing body of important literature that combines history and International Relations theory to create new perspectives on East Asian political and strategic behavior. The book explores the strategic and institutional dynamics of international relations in East Asian history when imperial China was the undisputed regional hegemon, focusing in depth on two central aspects of Chinese hegemony at the time: the grand strategies China and its neighbors adopted in their strategic interactions, and the international institutions they engaged in to maintain regional order-including but not limited to the tribute system. Feng Zhang draws on both Chinese and Western intellectual traditions to develop a relational theory of grand strategy and fundamental institutions in regional relations. The theory is evaluated with three case studies of Sino-Korean, Sino-Japanese, and Sino-Mongol relations during China's early Ming dynasty-when a type of Confucian expressive strategy was an essential feature of regional relations. He then explores the policy implications of this relational model for understanding and analyzing contemporary China's rise and the changing East Asian order. The book suggests some historical lessons for understanding contemporary Chinese foreign policy and considers the possibility of a more relational and cooperative Chinese strategy in the future.

This book describes the most frequently used high-speed serial buses in embedded systems, especially those used by FPGAs. These buses employ SerDes, JESD204, SRIO, PCIE, Aurora and SATA protocols for chip-to-chip and board-to-board communication, and CPCIE, VPX, FC and Infiniband protocols for inter-chassis communication. For each type, the book provides the bus history and version info, while also assessing its advantages and limitations. Furthermore, it offers a detailed guide to implementing these buses in FPGA design, from the physical layer and link synchronization to the frame format and application command. Given its scope, the book offers a valuable resource for researchers, R&D engineers and graduate students in computer science or electronics who wish to learn the protocol principles, structures and applications of high-speed serial buses.

This book constitutes the proceedings of the 15th IFIP International Conference on Network and Parallel Computing, NPC 2018, held in Muroran, Japan, in November/December 2018. The 22 full and 12 short papers presented in this volume were carefully reviewed and selected from 72 submissions. The papers cover traditional areas of network and parallel computing, including parallel applications, distributed algorithms, parallel architectures, software environments, and distributed tools.

This book presents recently developed methodologies that utilize quantized information in system identification and explores their potential in extending control capabilities for systems with limited sensor information or networked systems. The results of these methodologies can be applied to signal processing and control design of communication and computer networks, sensor networks, mobile agents, coordinated data fusion, remote sensing, telemedicine, and other fields in which noise-corrupted quantized data need to be processed.

System Identification with Quantized Observations is an excellent resource for graduate students, systems theorists, control engineers, applied mathematicians, as well as practitioners who use identification algorithms in their work.

A comparative exploration of Western and Chinese understandings of justice and their possible use to reframe Sino-American relations and international governance. The concept of justice is central to politics: it justifies the ordering of society and the distribution of rewards. In Justice and International Order, Richard Ned Lebow and Feng Zhang compare and contrast Western and Chinese conceptions of justice. They argue that justice can almost invariably be reduced to the principles of fairness and equality, although they are developed and expressed differently in the two cultures. Lebow and Zhang show that there has been a noticeable shift in both in favoring equality over fairness in the modern era. They analyze the growing conflict between China and the West in the light of these conceptions of justice and show how they might be deployed to ameliorate it. The authors also offer a critique of what passes for global order and explore ways in which fairness and equality, and trade-offs between them, offer pathways to better and more peaceful worlds.

This detailed volume collects protocols from scientists who are actively engaged in developing or using protoplast technology. The book begins with chapters that focus on basic protoplast techniques and their utilities, such as protocols on protoplast isolation, transfection, and regeneration, as well as examples of how to use protoplasts for genome editing and gene function analysis in a number of major crop or model plant species. It continues by exploring protoplast automation, large scale functional genomics, and synthetic biology. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  Authoritative and practical, Protoplast Technology: Methods and Protocols aims to inspire the new generation of researchers to further improve their protocols and apply this technology to accelerate the field of plant genomic study.

Multi-material 3D Printing Technology introduces the first models for complex construction and manufacturing using a multi-material 3D printer. The book also explains the advantages that these innovative models provide at various points of the manufacturing supply chain. Innovations in fields such as medicine and aerospace are seeing 3D printing applied to problems that require the technology to develop beyond its traditional definitions. This groundbreaking book provides broad coverage of the theory behind this emerging technology, and the technical details required for readers to investigate these methods for themselves. In addition to describing new models for application of this technology, this book also systematically summarizes the historical models, materials and relevant technologies that are important in multi-material 3D printing.

This book constitutes the refereed proceedings of the First International Workshop on Machine Learning and Medical Engineering for Cardiovasvular Healthcare, MLMECH 2019, and the International Joint Workshops on Computing and Visualization for Intravascular Imaging and Computer Assisted Stenting, CVII-STENT 2019, held in conjunction with MICCAI 2019, in Shenzhen, China, in October 2019. For MLMECH 2019, 16 papers were accepted for publication from a total of 21 submissions. They focus on machine learning techniques and analyzing of ECG data in the diagnosis of heart diseases. CVII-STENT 2019 accepted all 8 submissiones for publication. They contain technological and scientific research concerning endovascular procedures.

Competition between America and China has intensified since 2009, creating even greater risks of conflict. Why is this so and what can be done about it? In Taming Sino-American Rivalry, Feng Zhang and Richard Ned Lebow reject the prevailing idea that competition between a dominant and a rising power must necessarily lead to conflict. Rather, they identify the mistakes that both countries have made and explain the causes and consequences of their missteps. Drawing on international relations theory and lessons from history, they develop a comprehensive approach to conflict management and resolution that balances deterrence, reassurance, and diplomacy. A challenge to the prevailing pessimism, Taming Sino-American Rivalry is essential reading for anyone interested in understanding the world's most important bilateral relationship.